| Type | Description |
|---|---|
| Definition | WD repeat domain 45B |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:28:00 | Multi-site-mediated entwining of the linear WIR-motif around WIPI beta-propellers for autophagy. | 32483132 |
| 2019-08-03 10:08:00 | WDR45B has been identified as a potential intellectual disability gene through genomic sequencing of 2 large cohorts of affected individuals. In this report we present 6 individuals from 3 unrelated families with homozygous pathogenic variants in WDR45B: c.799C>T (p.Q267*) in 1 family and c.673C>T (p.R225*) in 2 families | 28503735 |
| 2018-12-22 11:40:00 | WIPI3 and WIPI4 beta-propellers have roles as scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy | 28561066 |
| Type | IDs |
|---|---|
| Synonymous | NEDSBAS, WDR45L, WIPI-3, WIPI3 |
| Gene |
UniProtKB-ID:
WIPI3_HUMAN
UniprotKB:
Q5MNZ6
UniParc:
UPI000020051D
EMBL:
AM182326,
AC124283,
AF091083,
CR456770,
AY691427,
KX434429,
CH471099
Ensembl:
ENSG00000141580
KO:
hsa:56270
|
| Nucleutide sequences |
EMBL-CDS:
ASF79340.1,
CAJ57996.1,
EAW89812.1,
AAC72952.1,
CAG33051.1,
AAV80763.1,
EAW89810.1
Ensembl_TRS:
ENST00000392325
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000376139
RefSeq:
XP_005256434.1,
XP_024306604.1,
XP_016880351.1,
NP_062559.2,
XP_016880352.1
|
| Others |
UniRef100:
UniRef100_Q5MNZ6
UniRef90:
UniRef90_Q5MNZ6
UniRef50:
UniRef50_Q5MNZ6
UniGene:
Hs.132161
CCDS:
CCDS11815.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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