| Type | Description |
|---|---|
| Definition | PROP paired-like homeobox 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 11:25:00 | A summary of phenotypes in patients with combined pituitary hormone deficiency caused by PROP1 mutations (Review). | 31090814 |
| 2018-07-07 11:26:00 | PROP1 mutations are a prevalent cause of congenital CPHD with OPP, and therefore, PROP1 sequencing must be the first step of molecular investigation in patients with CPHD and OPP, especially in populations with a high frequency of PROP1 mutations. | 28734020 |
| 2018-05-19 11:27:00 | Deletion in the PROP1 gene is associated with Combined pituitary hormone deficiency. | 28356564 |
| 2017-11-11 12:37:00 | The anterior pituitary gland comprised specialized cell-types that arise from stem cells expressing SOX2 and PROP1, which is necessary to establish the stem cell pool and promote an epithelial to mesenchymal-like transition, releasing progenitors from the niche. [review] | 27650955 |
| 2017-04-08 11:39:00 | GH replacement successfully corrects the growth deficit in children with Growth Hormone Deficiency . While the genetic aetiology remains undefined in most cases of Isolated Growth Hormone Deficiency , PROP1 mutations constitute a major cause for Multiple Pituitary Hormone Deficiencies. Persistence of Growth Hormone Deficiency into adulthood is related to abnormal pituitary morphology. | 27487097 |
| Type | IDs |
|---|---|
| Synonymous | CPHD2, PROP-1 |
| Gene |
UniProtKB-ID:
PROP1_HUMAN,
A0A0G2JQ02_HUMAN
UniprotKB:
O75360,
A0A0G2JQ02
UniParc:
UPI00001321A9,
UPI00001AEEA4
EMBL:
BC069076,
AF076214,
AF076215,
AC136940,
AF041141,
AF041140,
CH471390,
AF041139,
AC236592
Ensembl:
ENSG00000274382,
ENSG00000175325
KO:
hsa:5626
|
| Nucleutide sequences |
EMBL-CDS:
AAC77454.1,
AAH69076.1,
AAC77453.1,
AAC27900.1,
EAW50395.1
Gene_ORFName:
hCG_40268
Ensembl_TRS:
ENST00000308304,
ENST00000614006
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000311290,
ENSP00000484677
RefSeq:
NP_006252.4
|
| Others |
UniRef100:
UniRef100_A0A0G2JQ02,
UniRef100_O75360
UniRef90:
UniRef90_O75360
UniRef50:
UniRef50_O75360
UniGene:
Hs.158301
CCDS:
CCDS4430.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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