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56257 MEPCE

56257

MEPCE

methylphosphate capping enzyme

protein-coding

Homo sapiens

基因描述

Type Description
Definition methylphosphate capping enzyme

研究结论

Date Results Publications
2020-09-26 13:02:00 HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb. 31590891
2019-05-25 11:08:00 our results suggest that crosstalk between the histone-binding and RNA methylation activities of MePCE regulates P-TEFb activation on chromatin in a 7SK- and Brd4-independent manner. 29425494
2017-07-01 11:47:00 The 7SK small nuclear RNP (snRNP), composed of the 7SK small nuclear RNA (snRNA), MePCE, and Larp7, also functions as a canonical transcription factor that, in collaboration with the little elongation complex (LEC) comprising ELL, Ice1, Ice2, and ZC3H8, promotes transcription of RNAPII-specific spliceosomal snRNA and small nucleolar RNA (snoRNA) genes. 28254838
2016-06-28 11:00:00 Data indicate the binding of RNA-binding protein HEXIM with 7SKsnRNP complex comprising the non-coding RNA 7SK and proteins MePCE and 25863285
2010-01-21 00:00:00 Capping enzyme can play a direct role in transcription by modulating displacement of nascent RNA during transcription. 17978174

名称对应

Type IDs
Synonymous BCDIN3
Gene
UniProtKB-ID: MEPCE_HUMAN
UniprotKB: Q7L2J0
UniParc: UPI0000049FBB, UPI0000227DFA
EMBL: AF264752, CH236956, AK055964, BC018935, BC000556, CH471091, AK000264, BC016396, AC092849
Ensembl: ENSG00000146834
KO: hsa:56257
Nucleutide sequences
EMBL-CDS: AAH16396.1, EAW76536.1, EAW76535.1, AAH00556.2, BAA91040.1, EAL23834.1, BAG51598.1, AAF74767.1, EAW76534.1, AAH18935.2
Ensembl_TRS: ENST00000414441, ENST00000310512
Protein sequencees
Ensembl_PRO: ENSP00000400875, ENSP00000308546
RefSeq: NP_001181920.1, NP_001350415.1, NP_062552.2, NP_001181921.1, NP_001181919.1
Others
UniRef100: UniRef100_Q7L2J0
UniRef90: UniRef90_Q7L2J0
UniRef50: UniRef50_Q7L2J0
UniGene: Hs.178011
CCDS: CCDS5693.1, CCDS55136.1

全选

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