| Type | Description |
|---|---|
| Definition | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
| Date | Results | Publications |
|---|---|---|
| 2017-09-02 12:35:00 | Pals1 haploinsufficiency in mouse kidneys associated with the upregulation of Hippo pathway target genes and marker genes of TGF-beta signaling, including biomarkers of renal diseases. These findings support a link between apical polarity proteins and renal diseases, especially renal cyst diseases | 28154200 |
| 2016-07-30 11:19:00 | This study identifies Pals1 as a novel intrinsic factor that regulates the generation of cerebellar cells and Pals1 deficiency as a potential inhibitor of overactive mitogenic signaling. | 26657772 |
| 2015-10-10 10:54:00 | This paper reveals the role of the canonical polarity protein Pals1 in radial sorting of axons by Schwann cells. | 26203142 |
| 2012-10-13 10:09:00 | Data show the deletion of Pals1 leads to the disruption of the apical localization of Crb polarity complex proteins Crb1, Crb2 and Crb3 in retinal progenitors and the adult retina. | 22398208 |
| 2010-05-10 12:07:00 | Genetic study demonstrates a near-complete abrogation of cortical development in the absence of the apical complex protein Pals1. Despite the absence of most cortical structures, Pals1 CKO mice survive and display relatively normal health. | 20399730 |
| Type | IDs |
|---|---|
| Synonymous | 3830420B02Rik, AI255216, AI644496, Pals1 |
| Gene |
UniProtKB-ID:
MPP5_MOUSE,
B2RRY4_MOUSE
UniprotKB:
Q9JLB2,
B2RRY4
UniParc:
UPI0000028D0D
EMBL:
BC138624,
AF199008
Ensembl:
ENSMUSG00000021112
KO:
mmu:56217
|
| Nucleutide sequences |
EMBL-CDS:
AAF63789.1,
AAI38625.1
Ensembl_TRS:
ENSMUST00000082024
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000080683
RefSeq:
XP_017170628.1,
XP_006516161.1,
XP_030102684.1,
XP_006516160.1,
NP_062525.1,
XP_036013431.1
|
| Others |
UniRef100:
UniRef100_Q9JLB2
UniRef90:
UniRef90_Q9JLB2
UniRef50:
UniRef50_Q9JLB2
UniGene:
Mm.425777
CCDS:
CCDS26001.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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