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56216 Stx1b

56216

Stx1b

syntaxin 1B

protein-coding

Mus musculus

基因描述

Type Description
Definition syntaxin 1B

研究结论

Date Results Publications
2021-01-02 12:51:00 Epilepsy-causing STX1B mutations translate altered protein functions into distinct phenotypes in mouse neurons. 32572454
2018-07-21 10:40:00 Stx1b+/- mice exhibited reduced GABA release both in vitro and in vivo, disrupting the DAergic system in the CNS. Stx1b+/- mice exhibited reduced pre-pulse inhibition. 29139159
2016-07-16 11:36:00 Results demonstrated that STX1B is essential for the survival of neurons in vitro and it is a critical syntaxin protein for the neurotransmission at the mouse neuromuscular junctions 26203110
2014-11-08 11:54:00 Although STX1A and STX1B share a basic function as neuronal t-SNAREs, STX1B but not STX1A is necessary for the regulation of spontaneous and evoked synaptic vesicle exocytosis in fast transmission. 24587181
2014-10-04 11:45:00 STX1B was important for neuronal survival, possibly by regulating the secretion of neurotrophic factors 24666284

名称对应

Type IDs
Synonymous Stx1b2, Stx1bl, Syn1b
Gene
UniProtKB-ID: STX1B_MOUSE
UniprotKB: P61264
UniParc: UPI0000000C13
EMBL: D45207, D29743, BC132042, BC132068, AC149222
Ensembl: ENSMUSG00000030806
KO: mmu:56216
Nucleutide sequences
EMBL-CDS: AAI32069.1, BAA06162.1, AAI32043.1, BAA25986.1
Ensembl_TRS: ENSMUST00000106267
Protein sequencees
Ensembl_PRO: ENSMUSP00000101874
RefSeq: XP_011240168.1, XP_036009162.1, XP_006508107.1, NP_077725.1
Others
UniRef100: UniRef100_P61266
UniRef90: UniRef90_P61266
UniRef50: UniRef50_P61266
UniGene: Mm.439759
CCDS: CCDS40146.1

全选

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研究热度

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