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561970 adgrg6

561970

adgrg6

adhesion G protein-coupled receptor G6

protein-coding

Danio rerio

基因描述

Type Description
Definition adhesion G protein-coupled receptor G6

研究结论

Date Results Publications
2020-04-04 11:43:00 Alternative splicing regulates ECR conformation and receptor signaling, while mutagenesis of the calcium-binding site abolishes Gpr126 function in vivo. These results demonstrate that Gpr126 ECR utilizes a multi-faceted dynamic approach to regulate receptor function and provide relevant insights for ECR-targeted drug design. 31924782
2015-04-18 12:42:00 A new zebrafish mutation that truncates Gpr126 disrupted development of peripheral nerves and the inner ear. 25118328
2015-02-14 11:44:00 GPR126 modulates both physiological and pathological angiogenesis through VEGF signaling 25217645
2013-12-14 12:02:00 a model in which the NTF of Gpr126, in contrast to the C-terminal fragment, plays an important role in heart development. 24082093
2013-12-14 11:26:00 Gpr126 acts through a cAMP-mediated pathway to control the outgrowth and adhesion of canal projections in the zebrafish ear via the regulation of extracellular matrix gene expression. 24067352

名称对应

Type IDs
Synonymous gpr126, si:ch211-202p1.3
Gene
UniProtKB-ID: AGRG6_DANRE
UniprotKB: C6KFA3
UniParc: UPI0001AB0302
EMBL: GQ202546
KO: dre:561970
Nucleutide sequences
EMBL-CDS: ACS94979.1
Protein sequencees
RefSeq: NP_001156763.1, NP_001356058.1
Others
UniRef100: UniRef100_C6KFA3
UniRef90: UniRef90_C6KFA3
UniRef50: UniRef50_C6KFA3
UniGene: Dr.76404

全选

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研究热度

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