| Type | Description |
|---|---|
| Definition | tyrosyl-DNA phosphodiesterase 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-06-02 10:32:00 | EMCV yields are significantly reduced during infection of mouse embryonic fibroblasts genetically ablated for TDP2. | 29353210 |
| 2017-06-10 11:04:00 | The results collectively provide a structural mechanism for Tdp2 engagement of heterogeneous DNA damage that causes Top2 poisoning. | 27060144 |
| 2016-12-17 11:28:00 | data show that TDP2 activity potentiates enterovirus infections and, in the case of coxsackievirus B3, is a required host function following virus infection of mouse cells | 26715620 |
| 2013-06-15 10:59:00 | our data reveal TDP2-mediated error-free NHEJ as an efficient and accurate mechanism to repair TOP2-induced DSBs | 23505375 |
| 2012-12-22 10:46:00 | Evidence implicates Tdp2 in the repair of Top1-mediated DNA damage in cultured cells and in vivo, in the absence of Tdp1. | 22740648 |
| Type | IDs |
|---|---|
| Synonymous | D13Ertd656e, Ttrap |
| Gene |
UniProtKB-ID:
TYDP2_MOUSE
UniprotKB:
Q9JJX7
UniParc:
UPI0000024587
EMBL:
CH466561,
BC132511,
AJ251328,
BC132513,
AL589699
Ensembl:
ENSMUSG00000035958
KO:
mmu:56196
|
| Nucleutide sequences |
EMBL-CDS:
AAI32514.1,
CAB92971.1,
CAI26084.1,
EDL32475.1,
AAI32512.1
Ensembl_TRS:
ENSMUST00000038039
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035660
RefSeq:
NP_062424.1
|
| Others |
UniRef100:
UniRef100_Q9JJX7
UniRef90:
UniRef90_Q9JJX7
UniRef50:
UniRef50_Q9JJX7
UniGene:
Mm.427162
CCDS:
CCDS26381.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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