| Type | Description |
|---|---|
| Definition | protamine 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 10:46:00 | Study revealed that CA and AA genotypes in PRM1 gene were associated significantly with low sperm concentration and decreased sperm motility. Cases carrying A allele had a 6.05-fold increased risk for idiopathic infertility than cases carrying the C allele in a sample of Egyptian men. | 31286559 |
| 2018-12-22 11:35:00 | The expression level of PRM1 was significantly higher in colon cancer tissues and the staining degree of PRM1 in poorly-differentiated was stronger. | 29140788 |
| 2018-09-22 10:16:00 | Bacterial infections have significant negative effects on sperm chromatin condensation and protamine P1/P2 ratio. | 28736810 |
| 2018-05-26 11:11:00 | Protamine-1 and protamine-2 mRNA levels as well as the protamine mRNA ratio and all routine semen parameters revealed significant differences between recurrent miscarriage couples and healthy volunteers. Values of protamine-1 and protamine-2 mRNAs were significantly higher and the protamine mRNA ratio was significantly lower in couples with recurrent miscarriage. | 28854581 |
| 2018-05-26 10:14:00 | examinded the association between protamine gene alleles (PRM1 c.-190C>A, PRM1 c.197G>T, and PRM2 c.248C>T), and YBX2 (c.187T>C and c.1095 + 16A>G) and male infertility. We found that the AA and CA genotypes of the PRM1 c.-190C>A polymorphism had a significant association with infertility (p < 0.001) and the AA genotype was also highly significantly associated with high sperm DNA damage (p < 0.001). | 29227750 |
| Type | IDs |
|---|---|
| Synonymous | CT94.1, P1 |
| Gene |
UniProtKB-ID:
HSP1_HUMAN,
Q3MN80_HUMAN
UniprotKB:
P04553,
Q3MN80
UniParc:
UPI000013F2EE
EMBL:
M60331,
AF215707,
AY651260,
S68144,
HM005404,
CH471112,
BT006746,
BC003673,
Z46940,
AK311987,
U15422,
Y00443,
AB281136,
M29706
Ensembl:
ENSG00000175646
KO:
hsa:5619
|
| Nucleutide sequences |
EMBL-CDS:
CAA87065.1,
AAA60191.1,
AAB29321.2,
AAP35392.1,
AAC50486.1,
AAH03673.1,
CAA68499.1,
AAF34620.1,
AAA63249.1,
BAG34926.1,
AEE61002.1,
AAX35688.1,
BAF36637.1,
EAW85157.1
Gene_ORFName:
hCG_15067
Ensembl_TRS:
ENST00000312511
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000310515
RefSeq:
NP_002752.1
|
| Others |
UniRef100:
UniRef100_P04553
UniRef90:
UniRef90_P04553
UniRef50:
UniRef50_P04553
UniGene:
Hs.2909
CCDS:
CCDS10547.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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