Prodh2 - proline dehydrogenase (oxidase) 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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56189 Prodh2

基因描述

Type	Description
Definition	proline dehydrogenase (oxidase) 2

研究结论

Date	Results	Publications
2019-05-04 10:23:00	Decreasing hepatic glycolate oxidase and HYPDH expression decreases oxalate excretion.	26655602
2014-08-09 11:08:00	The nutrient starvation elicits increased activity of mitochondrial proline oxidase/dehydrogenase (POX/PRODH) that is causal in triggering a induction of ATGL.	24096872
2010-01-21 00:00:00	study revealed that the expression of PO and PDH was regulated by HNF1alpha and HNF4alpha	15581617

名称对应

Type	IDs
Synonymous	2510028N04Rik, 2510038B11Rik, HYPDH, MmPOX, MmPOX1, POX1
Gene	UniProtKB-ID: HYPDH_MOUSE UniprotKB: Q8VCZ9 UniParc: UPI0000025D63 EMBL: AF222851, U80019, AK050141, BC018182 Ensembl: ENSMUSG00000036892 KO: mmu:56189
Nucleutide sequences	EMBL-CDS: AAH18182.1, AAF21466.1, AAQ13907.1, BAC34090.1 Ensembl_TRS: ENSMUST00000058280
Protein sequencees	Ensembl_PRO: ENSMUSP00000062214 RefSeq: XP_006540288.1, XP_006540284.1, XP_006540286.1, XP_006540287.1, NP_062419.2, XP_006540285.1
Others	UniRef100: UniRef100_Q8VCZ9 UniRef90: UniRef90_Q8VCZ9 UniRef50: UniRef50_Q9UF12 UniGene: Mm.270525 CCDS: CCDS21093.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
31821850	The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria. Biochim Biophys Acta Mol Basis Dis Brianna Buchalski , Kyle D Wood , Anil Challa , Sonia Fargue , Ross P Holmes , W Todd Lowther , John Knight	2020-03-01	-
26655602	Metabolism of (13)C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase. Biochim. Biophys. Acta Xingsheng Li , John Knight , Sonia Fargue , Brianna Buchalski , Zhengrong Guan , Edward W Inscho , Abigail Liebow , Kevin Fitzgerald , William Querbes , W Todd Lowther , Ross P Holmes	2016-02-01	-
24096872	Proline oxidase-adipose triglyceride lipase pathway restrains adipose cell death and tissue inflammation. Cell Death Differ. D Lettieri Barbato , K Aquilano , S Baldelli , S M Cannata , S Bernardini , G Rotilio , M R Ciriolo	2014-01-01	Prodh2, Pnpla2
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21677750	A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley	2011-06-15	-
21386911	Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS ONE Rathi D Thiagarajan , Kylie M Georgas , Bree A Rumballe , Emmanuelle Lesieur , Han Sheng Chiu , Darrin Taylor , Dave T P Tang , Sean M Grimmond , Melissa H Little	2011-01-01	1110002E22Rik, Emilin1, Itga9, Smek2, Slc17a3, Gpsm3, Me2, Kazald1, Aldh1l1, Ccdc86, Mybpc1, Npy, Slc18a1, Ugt2b37, Foxp2, Ace, Ehbp1l1, Slc13a3, Adcy8, Ambp, Acsm1, Apoa4, Nr2f2, Synpo2, Bmp2, C2, Cacnb4, Capg, Casp4, Entpd5, Cdh11, Cideb, Col3a1, Col9a1, Csrp1, Cyp1b1, Cyp4a10, Dkk1, Dpep1, S1pr3, Eya1, F10, Fbp2, Fbp1, Slc6a13, Gpd1, Gnb4, Gng2, Gpm6b, Gria4, Gk, Hdc, Hhex, Hoxa10, Hpgd, Hpn, Elavl1, Elavl4, Igf1, Jag1, Napsa, Khsrp, Aff3, Lgals1, Lhx1, Stard4, Rbm39, Ly86, Edaradd, Kitl, Mlf1, Nxph1, Slc22a6, Pdgfra, Pgf, Prlr, Pipox, Ptn, Ttc36, Rem1, Rgs5, Nr1h4, Scnn1b, Sord, Sema3b, Slc23a1, Slc3a1, Serpini1, Stc2, Clic6, Tcn2, Tdrd5, Rassf2, Mfsd4b1, BC089597, Myo15b, Serpina10, Tgfb1i1, Tgfbi
19000842	Atlas of gene expression in the developing kidney at microanatomic resolution. Dev. Cell Eric W Brunskill , Bruce J Aronow , Kylie Georgas , Bree Rumballe , M Todd Valerius , Jeremy Aronow , Vivek Kaimal , Anil G Jegga , Jing Yu , Sean Grimmond , Andrew P McMahon , Larry T Patterson , Melissa H Little , S Steven Potter	2008-11-01	-
18614015	A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha	2008-07-11	Acacb, Hscb, Gadd45gip1, Lars2, Acad11, Chchd10, Nt5dc3, Slc25a41, Nt5m, Cyp27a1, Acly, Ndufb11, Gldc, Rexo2, Rars, Aldh6a1, Slc25a47, Rdh14, Ppif, Ldhal6b, Me2, Glyat, Slc25a45, Acaca, Nt5c3, Mrpl10, Mrpl41, Mrpl30, Aldh1l1, Mthfs, Shmt2, Atic, Mthfd1, Mat2b, Fam210a, Gpt2, Lyrm2, Rdh13, Mtrf1l, Atad3a, Rars2, Sccpdh, Me3, Maob, Dut, Cyp11b1, Fdps, Akr7a5, Msra, Krt5, Cox6b1, Qdpr, Acat1, Acat2, Aldh7a1, Pcca, Etfb, Etfa, Nudt19, Acadl, Acadm, Acadvl, Acaa1a, Acads, Aco1, Aco2, Prosc, Afg3l1, Adsl, Agxt, Ak2, Ak4, Akap1, Alas1, Alas2, Abcd1, Aldh2, Aldh3a2, Gfer, Acsm1, Slc25a4, Slc25a5, Prdx3, Prdx6, Mrps2, Arg2, Rhoa, Atp5a1, Atp5b, Atp5c1, Atp5f1, Atp5g1, Atp5j, Atp5k, Atpif1, Auh, Akr1b7, Bad, Bak1
18287559	GUDMAP: the genitourinary developmental molecular anatomy project. J Am Soc Nephrol Andrew P McMahon , Bruce J Aronow , Duncan R Davidson , Jamie A Davies , Kevin W Gaido , Sean Grimmond , James L Lessard , Melissa H Little , S Steven Potter , Elizabeth L Wilder , Pumin Zhang , GUDMAP project	2008-04-01	-
18554416	Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. Brad G Hoffman , Bogard Zavaglia , Joy Witzsche , Teresa Ruiz de Algara , Mike Beach , Pamela A Hoodless , Steven J M Jones , Marco A Marra , Cheryl D Helgason	2008-01-01	Fam174b, Ugt2b34, Emilin1, Akap9, Hepacam2, Cyp4v3, Lars2, Gck, Acly, Ces1d, Mycbpap, Fam110c, Card10, Arap3, Fam111a, Ssr1, Ankrd1, Ltbp4, Cald1, Ctrl, Cpa1, Clps, Vimp, Cela1, Fgb, Rap1gap, Acadl, Ace, Acp5, Chrna1, Tle6, Actc1, Actn2, Acta2, Adamts1, Adcy7, Plin2, Afp, Alcam, Ambp, Mat1a, Amy1, Anxa3, Anxa4, Ap1g2, Aplp1, Apoa1, Apoa2, Aqp1, Arc, Arg1, Arx, Ass1, Neurod4, Neurog3, Atp2a2, Bcap29, Bex2, Bgn, Klf5, Btg2, Btk, Serping1, Calca, Calm1, Calm2, Casp3, Serpina6, Cck, Cckar, Cd2ap, Cd34, Cd44, Cdk11b, Cdh1, Cdkn1a, Cdkn1c, Cel, Cfh, Chga, Chgb, Cited1, Cldn3, Clu, Cnih1, Plk3, Col14a1, Col15a1, Col3a1, Col5a2, Col6a1, Col9a2, Col1a1, Col1a2, Coq7, Cox6a2, Crabp2, Cryba2, Dnajc5

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