Type | Description |
---|---|
Definition | FXYD domain-containing ion transport regulator 1 |
Date | Results | Publications |
---|---|---|
2020-08-13 17:13:00 | Total FXYD1 subunit (modulates Na,K-ATPase activity) abundance was decreased in both mouse models | 32293933 |
2019-09-28 10:59:00 | Authors studied the male progeny of Fxyd1 null males bred to heterozygous Mecp2 female mice. Maximal NKA enzymatic activity was not altered by the loss of MeCP2, but it increased in mice lacking one Fxyd1 allele, suggesting that NKA activity is under Fxyd1 inhibitory control. | 29902467 |
2017-12-23 11:48:00 | It was proposed that FXYD1 plays a role in regulating AQP2 retention in apical membrane, and that this involves transfers between raft-like membrane domains in endosomes and plasma membranes. | 29155857 |
2016-04-09 10:04:00 | Both the extracellular PFXYD motif and the transmembrane domain of PLM but not the cytoplasmic tail were necessary for regulation of peak L-type Ca(2+) current amplitude. | 25918050 |
2015-06-20 10:45:00 | Decreased phosphorylation of PLM reduces Na/K pump activity and exacerbates Na overload, contractile dysfunction, and adverse remodelling following aortic constriction in mice. | 25103111 |
Type | IDs |
---|---|
Synonymous | 0610012C17Rik, 1110006M24Rik, Plm, Pml |
Gene |
UniProtKB-ID:
PLM_MOUSE
UniprotKB:
Q9Z239
UniParc:
UPI00000019ED
EMBL:
AF091390,
BC024671,
AK002585,
AF089734
Ensembl:
ENSMUSG00000036570
KO:
mmu:56188
|
Nucleutide sequences |
EMBL-CDS:
AAH24671.1,
AAD11781.1,
AAD41683.1,
BAB22208.1
Ensembl_TRS:
ENSMUST00000206860,
ENSMUST00000039909,
ENSMUST00000205778,
ENSMUST00000108110,
ENSMUST00000205439,
ENSMUST00000206474,
ENSMUST00000206328,
ENSMUST00000206012,
ENSMUST00000071697,
ENSMUST00000206305
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103745,
ENSMUSP00000145818,
ENSMUSP00000048460,
ENSMUSP00000145589,
ENSMUSP00000145920,
ENSMUSP00000071617,
ENSMUSP00000145712,
ENSMUSP00000146288,
ENSMUSP00000146064,
ENSMUSP00000146295
RefSeq:
XP_006540282.2,
NP_062376.2,
XP_011248954.1,
NP_443717.1,
XP_011248952.1,
XP_011248950.1,
XP_011248951.1,
NP_919302.1,
NP_443718.1,
XP_030098669.1,
XP_030098668.1,
XP_011248953.1
|
Others |
UniRef100:
UniRef100_Q9Z239
UniRef90:
UniRef90_Q9Z239
UniRef50:
UniRef50_O00168
UniGene:
Mm.1491
CCDS:
CCDS21123.1
|
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