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5618 PRLR

5618

PRLR

prolactin receptor

protein-coding

Homo sapiens

基因描述

Type Description
Definition prolactin receptor

研究结论

Date Results Publications
2020-12-12 13:23:00 Association between prolactin receptor expression and proliferation in the endometrium of obese women with polycystic ovary syndrome. 31389293
2020-12-05 12:59:00 Prolactin Acts on Myeloid Progenitors to Modulate SMAD7 Expression and Enhance Hematopoietic Stem into the NK 32286456
2020-03-28 10:30:00 PRLR probably plays a different role in the development and progression of breast cancer. In luminal A and luminal B HER2-positive subtypes PRLR may act as an oncogen, and in luminal B HER2-negative and ER-, PR-negative subtypes can play a tumor suppressor role. 32116231
2020-03-14 12:27:00 our results identify an association between a gain-of-function PRLR variant and prolactinomas and reveal a new etiology and potential therapeutic approach for these neoplasms. 30445560
2019-11-30 11:48:00 Prolactin-PRLR signaling may play a crucial role for the progression of type I endometrial cancer (EC) without involving the PTEN mutation in young hyperprolactinemic women without insulin resistance. 29901521

名称对应

Type IDs
Synonymous HPRL, MFAB, RI-PRLR, hPRLrI
Gene
UniProtKB-ID: PRLR_HUMAN
UniprotKB: P16471
UniParc: UPI000006E763, UPI000006CDDA, UPI0000070905, UPI0000132234, UPI00004C2D3D, UPI000006E673, UPI000002B196, UPI0001BDA954, UPI000006D8E7
EMBL: AK313270, AF091867, AF091868, AC010368, AF416618, AF091865, S78505, AF416619, AF091864, GU133399, BC059392, AF091866, AF091863, AF493069, AF091870, AF091869, AF166329, CH471119, M31661, AF349939, AC091851, AF492470
Ensembl: ENSG00000113494
KO: hsa:5618
Nucleutide sequences
EMBL-CDS: AAA60174.1, ACZ04321.1, BAG36079.1, EAW55919.1, AAM11661.1, AAK32703.1, AAD49855.1, AAL23914.1, AAM18048.1, AAH59392.1, AAL23915.1, AAB34470.1, AAD32032.1
Ensembl_TRS: ENST00000511486, ENST00000514088, ENST00000231423, ENST00000542609, ENST00000509140, ENST00000620785, ENST00000513753, ENST00000348262, ENST00000618457, ENST00000310101, ENST00000619676
Protein sequencees
Ensembl_PRO: ENSP00000424841, ENSP00000482954, ENSP00000441813, ENSP00000482689, ENSP00000311613, ENSP00000484768, ENSP00000231423, ENSP00000422556, ENSP00000422935, ENSP00000309008, ENSP00000425300
RefSeq: NP_001191243.1, NP_001191246.1, XP_016865134.1, XP_024301900.1, XP_024301899.1, XP_011512371.1, XP_011512370.1, NP_001191244.1, NP_000940.1, XP_006714547.1, NP_001191247.1, NP_001191245.1
Others
UniRef100: UniRef100_P16471
UniRef90: UniRef90_P16471
UniRef50: UniRef50_P16471
UniGene: Hs.368587, Hs.602914
CCDS: CCDS56359.1, CCDS56361.1, CCDS56358.1, CCDS3909.1, CCDS56360.1, CCDS56362.1

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