| Type | Description |
|---|---|
| Definition | gasdermin C |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:34:00 | Two GWAS-identified variants are associated with lumbar spinal stenosis and Gasdermin-C expression in Chinese population. | 33273635 |
| 2020-12-12 13:29:00 | PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. | 32929201 |
| 2020-11-21 13:24:00 | Overexpression of GSDMC is a prognostic factor for predicting a poor outcome in lung adenocarcinoma. | 31939622 |
| 2019-01-26 11:39:00 | These data suggested that TRPV1 may serve an important role in the induction of GSDMC expression by UV and that UVinduced GSDMC expression may be mediated via a calcium/calcineurin/NFATc1 pathway. | 30226565 |
| 2018-09-22 11:19:00 | Expression of GSDMC is increased by UV irradiation in human skin keratinocytes. GSDMC induction contributes to the increase of MMP-1 expression specifically via activation of ERK and JNK pathways. | 29428815 |
| Type | IDs |
|---|---|
| Synonymous | MLZE |
| Gene |
UniProtKB-ID:
GSDMC_HUMAN
UniprotKB:
Q9BYG8
UniParc:
UPI0000071445
EMBL:
BC063595,
AB042405,
AC022849,
BC035321
Ensembl:
ENSG00000147697
KO:
hsa:56169
|
| Nucleutide sequences |
EMBL-CDS:
AAH35321.1,
AAH63595.1,
BAB40331.1
Ensembl_TRS:
ENST00000276708,
ENST00000619643
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000482343,
ENSP00000276708
RefSeq:
XP_011515460.1,
NP_113603.1,
XP_011515469.1,
XP_011515461.1,
XP_011515464.1,
XP_011515467.1,
XP_011515463.1,
XP_011515465.1,
XP_011515470.1,
XP_011515468.1,
XP_016869134.1
|
| Others |
UniRef100:
UniRef100_Q9BYG8
UniRef90:
UniRef90_Q9BYG8
UniRef50:
UniRef50_Q9BYG8
UniGene:
Hs.133244
CCDS:
CCDS6360.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33273635 |
Sci Rep Hua Jiang , Abu Moro , Yang Liu , Jiaqi Wang , Dihua Meng , Xinli Zhan , Qingjun Wei |
2020-12-03 | - |
| 32929201 |
Nat Cell Biol Junwei Hou , Rongce Zhao , Weiya Xia , Chiung-Wen Chang , Yun You , Jung-Mao Hsu , Lei Nie , Yeh Chen , Yu-Chuan Wang , Chunxiao Liu , Wei-Jan Wang , Yun Wu , Baozhen Ke , Jennifer L Hsu , Kebin Huang , Zu Ye , Yi Yang , Xianghou Xia , Yintao Li , Chia-Wei Li , Bin Shao , John A Tainer , Mien-Chie Hung |
2020-10-01 | - |
| 31939622 |
Overexpression of GSDMC is a prognostic factor for predicting a poor outcome in lung adenocarcinoma. Mol Med Rep Jie Wei , Zhijie Xu , Xi Chen , Xiang Wang , Shuangshuang Zeng , Long Qian , Xue Yang , Chunlin Ou , Wei Lin , Zhicheng Gong , Yuanliang Yan |
2020-01-01 | - |
| 30226565 |
Int. J. Mol. Med. Novi Kusumaningrum , Dong Hun Lee , Hyun-Sun Yoon , Chi-Hyun Park , Jin Ho Chung |
2018-11-01 | - |
| 29676528 |
E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. FEBS J. Richa Khanna , Vidhya Krishnamoorthy , Veena K Parnaik |
2018-06-01 | - |
| 29428815 |
J. Dermatol. Sci. Novi Kusumaningrum , Dong Hun Lee , Hyun-Sun Yoon , Yeon Kyung Kim , Chi-Hyun Park , Jin Ho Chung |
2018-05-01 | - |
| 27835699 |
PLoS ONE Masashi Miguchi , Takao Hinoi , Manabu Shimomura , Tomohiro Adachi , Yasufumi Saito , Hiroaki Niitsu , Masatoshi Kochi , Haruki Sada , Yusuke Sotomaru , Tsuneo Ikenoue , Kunitoshi Shigeyasu , Kohji Tanakaya , Yasuhiko Kitadai , Kazuhiro Sentani , Naohide Oue , Wataru Yasui , Hideki Ohdan |
2016-01-01 | - |
| 25429064 |
Hum. Mol. Genet. Meian He , Min Xu , Ben Zhang , Jun Liang , Peng Chen , Jong-Young Lee , Todd A Johnson , Huaixing Li , Xiaobo Yang , Juncheng Dai , Liming Liang , Lixuan Gui , Qibin Qi , Jinyan Huang , Yanping Li , Linda S Adair , Tin Aung , Qiuyin Cai , Ching-Yu Cheng , Myeong-Chan Cho , Yoon Shin Cho , Minjie Chu , Bin Cui , Yu-Tang Gao , Min Jin Go , Dongfeng Gu , Weiqiong Gu , Huan Guo , Yongchen Hao , Jie Hong , Zhibin Hu , Yanling Hu , Jianfeng Huang , Joo-Yeon Hwang , Mohammad Kamran Ikram , Guangfu Jin , Dae-Hee Kang , Chiea Chuen Khor , Bong-Jo Kim , Hung Tae Kim , Michiaki Kubo , Jeannette Lee , Juyoung Lee , Nanette R Lee , Ruoying Li , Jun Li , JianJun Liu , Jirong Longe , Wei Lu , Xiangfeng Lu , Xiaoping Miao , Yukinori Okada , Rick Twee-Hee Ong , Gaokun Qiu , Mark Seielstad , Xueling Sim , Huaidong Song , Fumihiko Takeuchi , Toshihiro Tanaka , Phil R Taylor , Laiyuan Wang , Weiqing Wang , Yiqin Wang , Chen Wu , Ying Wu , Yong-Bing Xiang , Ken Yamamoto , Handong Yang , Ming Liao , Mitsuhiro Yokota , Terri Young , Xiaomin Zhang , Norihiro Kato , Qing K Wang , Wei Zheng , Frank B Hu , Dongxin Lin , Hongbing Shen , Yik Ying Teo , Zengnan Mo , Tien Yin Wong , Xu Lin , Karen L Mohlke , Guang Ning , Tatsuhiko Tsunoda , Bok-Ghee Han , Xiao-Ou Shu , E Shyong Tai , Tangchun Wu , Lu Qi |
2015-03-15 |
LOC101927898,
SLC17A2,
CNPY2,
ANAPC10,
FBLN5,
UBD,
FRS2,
ATF7,
NUDT3,
CEP250,
DIS3L2,
CSH1,
ILF3-AS1,
CTBP2,
SLC23A3,
RASGEF1B,
SLC38A9,
CEP120,
CYP19A1,
DDX6,
QSOX2,
PSORS1C1,
ADAMTS17,
ACAN,
DNM2,
DNMT3A,
SDR16C5,
SPAG17,
EXTL3,
DLEU7,
EFEMP1,
ZNF438,
TWISTNB,
GPC5,
KDM6B,
FBXW11,
ATP13A2,
RYBP,
ZBTB38,
LCORL,
DNM3,
GHR,
GHSR,
FAM184B,
ZNF638,
GLI2,
GNA12,
HCG22,
HIST1H2AD,
HMGA1,
C17orf67,
CATSPER3,
IGF1,
IGF1R,
ILF3,
KCNQ1,
LIN28B,
FADS1,
LTBP1,
LTBP2,
MC4R,
MEF2C,
MAP3K3,
MFAP2,
MYC,
NPPC,
SIX6,
PARN,
CRIM1,
DNAJC27,
ATP5G2,
PITX1,
PLAG1,
POLR2B,
ZRANB1,
TET2,
DYM,
DCAF16,
UQCC1,
GSDMC,
ZMIZ1,
ADAMTSL3,
ADGRG6,
PTCH1,
MKL2,
ZFAT,
PTPN9,
PTPN14,
RBBP8,
RBL1,
CCND1,
REST,
PAPPA2,
NCAPG,
HHIP,
NARFL,
HHIP-AS1,
SHOX2,
FNDC3B
|
| 25281659 |
A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum Mol Genet Ralf J P van der Valk , Eskil Kreiner-Møller , Marjolein N Kooijman , Mònica Guxens , Evangelia Stergiakouli , Annika Sääf , Jonathan P Bradfield , Frank Geller , M Geoffrey Hayes , Diana L Cousminer , Antje Körner , Elisabeth Thiering , John A Curtin , Ronny Myhre , Ville Huikari , Raimo Joro , Marjan Kerkhof , Nicole M Warrington , Niina Pitkänen , Ioanna Ntalla , Momoko Horikoshi , Riitta Veijola , Rachel M Freathy , Yik-Ying Teo , Sheila J Barton , David M Evans , John P Kemp , Beate St Pourcain , Susan M Ring , George Davey Smith , Anna Bergström , Inger Kull , Hakon Hakonarson , Frank D Mentch , Hans Bisgaard , Bo Chawes , Jakob Stokholm , Johannes Waage , Patrick Eriksen , Astrid Sevelsted , Mads Melbye , Early Genetics and Lifecourse Epidemiology (EAGLE) Consortium , Cornelia M van Duijn , Carolina Medina-Gomez , Albert Hofman , Johan C de Jongste , H Rob Taal , André G Uitterlinden , Genetic Investigation of ANthropometric Traits (GIANT) Consortium , Loren L Armstrong , Johan Eriksson , Aarno Palotie , Mariona Bustamante , Xavier Estivill , Juan R Gonzalez , Sabrina Llop , Wieland Kiess , Anubha Mahajan , Claudia Flexeder , Carla M T Tiesler , Clare S Murray , Angela Simpson , Per Magnus , Verena Sengpiel , Anna-Liisa Hartikainen , Sirkka Keinanen-Kiukaanniemi , Alexandra Lewin , Alexessander Da Silva Couto Alves , Alexandra I Blakemore , Jessica L Buxton , Marika Kaakinen , Alina Rodriguez , Sylvain Sebert , Marja Vaarasmaki , Timo Lakka , Virpi Lindi , Ulrike Gehring , Dirkje S Postma , Wei Ang , John P Newnham , Leo-Pekka Lyytikäinen , Katja Pahkala , Olli T Raitakari , Kalliope Panoutsopoulou , Eleftheria Zeggini , Dorret I Boomsma , Maria Groen-Blokhuis , Jorma Ilonen , Lude Franke , Joel N Hirschhorn , Tune H Pers , Liming Liang , Jinyan Huang , Berthold Hocher , Mikael Knip , Seang-Mei Saw , John W Holloway , Erik Melén , Struan F A Grant , Bjarke Feenstra , William L Lowe , Elisabeth Widén , Elena Sergeyev , Harald Grallert , Adnan Custovic , Bo Jacobsson , Marjo-Riitta Jarvelin , Mustafa Atalay , Gerard H Koppelman , Craig E Pennell , Harri Niinikoski , George V Dedoussis , Mark I Mccarthy , Timothy M Frayling , Jordi Sunyer , Nicholas J Timpson , Fernando Rivadeneira , Klaus Bønnelykke , Vincent W V Jaddoe , Early Growth Genetics (EGG) Consortium |
2015-02-15 | - |
| 23393555 |
Genome-wide association study of retinopathy in individuals without diabetes. PLoS One Richard A Jensen , Xueling Sim , Xiaohui Li , Mary Frances Cotch , M Kamran Ikram , Elizabeth G Holliday , Gudny Eiriksdottir , Tamara B Harris , Fridbert Jonasson , Barbara E K Klein , Lenore J Launer , Albert Vernon Smith , Eric Boerwinkle , Ning Cheung , Alex W Hewitt , Gerald Liew , Paul Mitchell , Jie Jin Wang , John Attia , Rodney Scott , Nicole L Glazer , Thomas Lumley , Barbara McKnight , Bruce M Psaty , Kent Taylor , Albert Hofman , Paulus T V M de Jong , Fernando Rivadeneira , Andre G Uitterlinden , Wan-Ting Tay , Yik Ying Teo , Mark Seielstad , Jianjun Liu , Ching-Yu Cheng , Seang-Mei Saw , Tin Aung , Santhi K Ganesh , Christopher J O'Donnell , Mike A Nalls , Kerri L Wiggins , Jane Z Kuo , Blue Mountains Eye Study GWAS Team , CKDGen Consortium , Cornelia M van Duijn , Vilmundur Gudnason , Ronald Klein , David S Siscovick , Jerome I Rotter , E Shong Tai , Johannes Vingerling , Tien Y Wong |
2013-01-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员