| Type | Description |
|---|---|
| Definition | protein kinase X-linked |
| Date | Results | Publications |
|---|---|---|
| 2017-02-18 10:29:00 | PRKX, WNT3 and WNT16 genes, belonging to the WNT signaling pathway, are involved in the tumorigenic process of nodular basal cell carcinoma | 27630294 |
| 2016-12-17 11:52:00 | The characteristics and developmental functions of PRKX. [review] | 26252946 |
| 2012-11-24 10:05:00 | findings reveals a major role of PRKX, TTBK2 and RSK4 in triggering Sunitinib resistance formation; data suggest transcriptional regulation of these kinases together with other proteins might play an important role in formation of Sunitinib resistance by affecting transcription factors | 22020623 |
| 2012-02-25 11:27:00 | MBD 4--a potential substrate for protein kinase X | 21971312 |
| 2011-10-01 12:07:00 | The interaction of PRKX with Pin-1, Magi-1 and Bag-3 could contribute to the stimulating role of PRKX in angiogenesis. | 21684272 |
| Type | IDs |
|---|---|
| Synonymous | PKX1 |
| Gene |
UniProtKB-ID:
PRKX_HUMAN,
A0A024RBU5_HUMAN
UniprotKB:
P51817,
A0A024RBU5
UniParc:
UPI000000D998
EMBL:
X85545,
BC041073,
CH471074
Ensembl:
ENSG00000183943
KO:
hsa:5613
|
| Nucleutide sequences |
EMBL-CDS:
AAH41073.1,
CAA59733.1,
EAW98728.1,
EAW98727.1
Gene_ORFName:
hCG_18488
Ensembl_TRS:
ENST00000262848
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262848
RefSeq:
NP_005035.1
|
| Others |
UniRef100:
UniRef100_P51817
UniRef90:
UniRef90_P51817
UniRef50:
UniRef50_P51817
UniGene:
Hs.390788
CCDS:
CCDS14125.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28611215 |
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc. Natl. Acad. Sci. U.S.A. Teng Fei , Yiwen Chen , Tengfei Xiao , Wei Li , Laura Cato , Peng Zhang , Maura B Cotter , Michaela Bowden , Rosina T Lis , Shuang G Zhao , Qiu Wu , Felix Y Feng , Massimo Loda , Housheng Hansen He , X Shirley Liu , Myles Brown |
2017-06-27 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27630294 |
Altered Expression of PRKX, WNT3 and WNT16 in Human Nodular Basal Cell Carcinoma. Anticancer Res. Natalia Gurgel DO Carmo , Luis Henrique Toshihiro Sakamoto , Robert Pogue , Cintia DO Couto Mascarenhas , Simone Karst Passos , Maria Sueli Soares Felipe , Rosângela Vieira DE Andrade |
2016-09-01 | - |
| 26252946 |
PRKX, a Novel cAMP-Dependent Protein Kinase Member, Plays an Important Role in Development. J. Cell. Biochem. Sizhou Huang , Qian Li , Ian Alberts , Xiaohong Li |
2016-03-01 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 26673895 |
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife Koray Kırlı , Samir Karaca , Heinz Jürgen Dehne , Matthias Samwer , Kuan Ting Pan , Christof Lenz , Henning Urlaub , Dirk Görlich |
2015-01-01 |
CHA1,
KRR1,
SRO9,
STE50,
RRP7,
RNQ1,
DCC1,
GBP2,
SAT4,
RVS161,
YCR016W,
PWP2,
SSK22,
SOL2,
PAT1,
YCR087C-A,
OCA4,
MOB2,
EPL1,
BUD27,
FRS2,
LOC1,
YFR016C,
LSB3,
RPL2A,
PHO4,
SAP155,
IRC6,
ENT4,
PRP19,
RIX7,
YLL032C,
FRA1,
ISA1,
SPA2,
PUF3,
RPL8B,
NOC3,
SSL1,
SSK1,
NSE1,
RLP24,
SDO1,
ADE16,
RPL15A,
STU2,
RPS0B,
FRS1,
BMT6,
KIN2,
HRT3,
REX3,
YLR108C,
CFT2,
MSL5,
ACE2,
STM1,
YLR157C-A,
APS1,
CBF5,
SWI6,
SKG3,
HCR1,
PWP1,
NOP56,
BUR2,
GPN3,
DBP9,
GCD7,
SGD1,
STE11,
NMD4,
RPS22B,
ROM2,
STP3,
IKI3,
REH1,
AFG2,
UTP21,
ATG17,
TUS1,
MAG2,
ATG23,
RPS1A,
FPR4,
PDP3,
CDC24,
RBG1,
FUN12,
MTW1,
PRP45,
MAK16,
ECM1,
GPB2,
VPS8,
KIN3,
CDC15,
YAT1,
WHI4
|
| 22939624 |
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Cell Mikko Taipale , Irina Krykbaeva , Martina Koeva , Can Kayatekin , Kenneth D Westover , Georgios I Karras , Susan Lindquist |
2012-08-31 |
NR1H3,
TRIM10,
SGK2,
PREB,
CDK3,
TNK2,
CDK4,
CDK6,
CDK7,
CDK9,
LOC400927-CSNK1E,
PCGF3,
TESK2,
MERTK,
KAT5,
CEBPE,
NPRL2,
CAMKK2,
MAP3K2,
FASTK,
RCBTB2,
PIM2,
WWP1,
CHEK1,
CDC37,
MAP4K1,
IRAK3,
TP53RK,
STK38,
KLHL32,
KLHL29,
FBXO17,
CLK2,
CLK3,
FBXO27,
ASB17,
RNF19B,
ACVR1C,
GRK7,
MAP3K8,
ASB6,
MYO3B,
RAB40A,
CSF1R,
FBXL14,
CSNK1A1,
CSNK1E,
HIPK4,
PDIK1L,
KLHL23,
SH3RF2,
SGK223,
DAPK3,
DCLK2,
ZBTB49,
DLX6,
DMPK,
EGFR,
EPHA2,
EPHA1,
EPHA4,
EPHB1,
EPHB6,
ERBB2,
ERBB3,
ERBB4,
AKT2,
ESR1,
PTK2B,
FBXL13,
FER,
FES,
MAPK15,
FGFR1,
FGFR3,
FGR,
ICK,
TRIM32,
TCF25,
STK38L,
FOXM1,
MAST2,
PASK,
LARP4B,
FBXO28,
DTX4,
FLT4,
ZC3H7B,
FBXW11,
TRIM2,
SF3B3,
TSSK2,
SGK3,
ALK,
FRK,
ABL1,
FYN,
KLHL34,
FBXL2
|
| 22020623 |
Int. J. Cancer Claus Bender , Axel Ullrich |
2012-07-15 |
TTBK2,
RPS6KA6,
PRKX
|
| 21971312 |
MBD 4--a potential substrate for protein kinase X. Acta Biochim. Biophys. Sin. (Shanghai) Ying Lin , Wei Li |
2011-11-01 |
PRKX,
MBD4
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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