| Type | Description |
|---|---|
| Definition | DnaJ heat shock protein family (Hsp40) member C3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:51:00 | DNAJC3 deficiency induces beta-cell mitochondrial apoptosis and causes syndromic young-onset diabetes. | 33486469 |
| 2020-03-28 11:41:00 | DNAJC3-AS1 is up-regulated in osteosarcoma (OS) tissues and its high expression is associated with poor prognosis of OS patients. | 30652414 |
| 2018-10-13 11:49:00 | DNAJC3 p.H238N is likely to be a variant causing diabetes. | 29767246 |
| 2015-03-21 10:34:00 | p58IPK is a general inhibitor of the eIF2alpha kinases in that it also interacts with GCN2. Thus forced overexpression of cytoplasmic p58 delays eIF2alpha phosphorylation, suppresses GCN2 phosphorylation and prolongs protein synthesis | 25329545 |
| 2015-02-28 12:17:00 | Loss-of-function DNAJC3 mutations lead to a monogenic, recessive form of diabetes mellitus in humans. | 25466870 |
| Type | IDs |
|---|---|
| Synonymous | ACPHD, ERdj6, HP58, P58, P58IPK, PRKRI |
| Gene |
UniProtKB-ID:
DNJC3_HUMAN,
A8KA82_HUMAN
UniprotKB:
Q13217,
A8KA82
UniParc:
UPI000006F088
EMBL:
AK292947,
U28424,
AY795482,
BC047936,
AL138955,
CH471085,
AK312861
Ensembl:
ENSG00000102580
KO:
hsa:5611
|
| Nucleutide sequences |
EMBL-CDS:
AAC50502.1,
AAH47936.2,
AAV40838.1,
BAG35713.1,
EAX08959.1,
BAF85636.1
Gene_ORFName:
hCG_28703
Ensembl_TRS:
ENST00000602402
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000473631
RefSeq:
XP_011519406.1,
NP_006251.1,
XP_011519407.1,
XP_016876163.1,
XP_016876164.1
|
| Others |
UniRef100:
UniRef100_Q13217
UniRef90:
UniRef90_Q13217
UniRef50:
UniRef50_Q13217
UniGene:
Hs.59214
CCDS:
CCDS9479.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员