| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase 7 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:08:00 | A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation. | 32601196 |
| 2020-09-05 13:59:00 | An autophagy-related model of 4 key genes for predicting prognosis of patients with laryngeal cancer. | 32791689 |
| 2020-01-25 13:55:00 | MKK7 transcription, regulated by SP1 and KLF5, critically depends on HDAC4 activity. | 30963560 |
| 2019-12-14 12:25:00 | Both Src and MAPK are coactivated in 31% of high-grade serous ovarian cancer (HGSOC), and this associates with worse overall survival on multivariate analysis. Frequent dual kinase activation in HGSOC led us to assay the efficacy of combined Src and MEK inhibition | 29959144 |
| 2019-12-14 10:24:00 | Our preclinical study supports further clinical evaluation of combined MEK inhibition and chemotherapy for lung cancer patients harboring KRAS (G12C) and wild-type p53 status | 29945997 |
| Type | IDs |
|---|---|
| Synonymous | JNKK2, MAPKK7, MEK, MEK 7, MKK7, PRKMK7, SAPKK-4, SAPKK4 |
| Gene |
UniProtKB-ID:
MP2K7_HUMAN,
B4DV95_HUMAN
UniprotKB:
O14733,
B4DV95
UniParc:
UPI000015558E,
UPI00017A7E85,
UPI000012F494,
UPI000002AE47,
UPI00000742F6
EMBL:
AK300988,
AF013589,
CH471139,
AF022805,
AK313899,
AF003199,
AF013588,
AF006689,
DQ445915,
BC038295,
AF014401
Ensembl:
ENSG00000076984
KO:
hsa:5609
|
| Nucleutide sequences |
EMBL-CDS:
BAG36622.1,
AAC16272.1,
EAW68968.1,
AAC26142.1,
AAH38295.1,
AAC16273.1,
ABE03013.1,
AAB97813.1,
AAB63374.1,
AAB88048.1,
EAW68964.1,
BAG62607.1
Ensembl_TRS:
ENST00000397983,
ENST00000397979,
ENST00000397981
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000381068,
ENSP00000381070,
ENSP00000381066
RefSeq:
NP_660186.1,
NP_001284485.1,
XP_006722863.1,
NP_001284484.1
|
| Others |
UniRef100:
UniRef100_B4DV95,
UniRef100_O14733
UniRef90:
UniRef90_H0VZM8,
UniRef90_O14733
UniRef50:
UniRef50_Q8CE90-7,
UniRef50_O14733
UniGene:
Hs.531754
CCDS:
CCDS74278.1,
CCDS74277.1,
CCDS42491.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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