| Type | Description |
|---|---|
| Definition | transglutaminase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-18 10:58:00 | Immunofluorescence staining and western blot analyses demonstrated that Tgm2 overexpression had beneficial effects on the rate of Ectomesenchymal stem cells (EMSCs) neurogenesis, and that the proliferative capacity of Tgm2 EMSCs was higher than that of controls. | 31322240 |
| 2020-01-04 10:09:00 | Cultured Xbp1-deficient vascular smooth muscle cells (VSMCs) demonstrated decreased levels of TG2 protein, in association with increased TG2 polyubiquitination. Moreover, IRE1alpha, and TG2-specific transamidation cross-links were increased in carotid artery neointima in Xbp1fl/fl SM22alpha-CRE+ mice. Cultured TG2-deficient VSMCs had decreased Xbp1 associated with increased IRE1alpha, and increased migration in respons... | 30943188 |
| 2019-11-16 11:13:00 | Knockdown of TG2 resulted in a significant increase in cathepsin S expression, which precede the loss of neuronal viability. | 30239049 |
| 2019-03-23 12:29:00 | Our data show that under inflammatory conditions in vitro, TG2 production is enhanced in astrocytes and microglia. We observed that in particular, astrocytes produce fibronectin that can be cross-linked and aggregated by exogenous TG2. | 29282083 |
| 2018-07-21 11:54:00 | Transglutaminase 2 plays a crucial role in mediating neuronal survival through its regulation of genes involved in neurite length. | 29197584 |
| Type | IDs |
|---|---|
| Synonymous | TgaseII |
| Gene |
UniProtKB-ID:
Q6P6R6_RAT
UniprotKB:
Q6P6R6
UniParc:
UPI000021C5EB
EMBL:
BC062062
KO:
rno:56083
|
| Nucleutide sequences |
EMBL-CDS:
AAH62062.1
|
| Protein sequencees |
RefSeq:
NP_062259.3
|
| Others |
UniRef100:
UniRef100_Q6P6R6
UniRef90:
UniRef90_P21981
UniRef50:
UniRef50_P21980
UniGene:
Rn.10
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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