| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:18:00 | MEK5 promotes lung adenocarcinoma. | 30442718 |
| 2020-10-24 14:09:00 | The MEK5-ERK5 Kinase Axis Controls Lipid Metabolism in Small-Cell Lung Cancer. | 31969375 |
| 2020-07-11 12:46:00 | MEK5 is a novel autophagy modulator | 31005259 |
| 2019-09-14 11:34:00 | MAP2K5/SKOR1 may be associated with Chinese essential tremor patients. | 29798820 |
| 2019-06-08 12:33:00 | Study in Chinese familial non-medullary thyroid carcinoma patients revealed that MAP2K5 variants A321T or M367 T can activate MAP2K5-ERK5 pathway, alter downstream gene expression, and subsequently induce thyroid epithelial cell malignant transformation. | 30132833 |
| Type | IDs |
|---|---|
| Synonymous | HsT17454, MAPKK5, MEK5, PRKMK5 |
| Gene |
UniProtKB-ID:
MP2K5_HUMAN,
A0A024R5Y2_HUMAN,
A0A024R5X5_HUMAN
UniprotKB:
Q13163,
A0A024R5Y2,
A0A024R5X5
UniParc:
UPI0000072D4A,
UPI00017A6C66,
UPI000151DD9D,
UPI000012F490
EMBL:
U71088,
BC008838,
BT006780,
AK293459,
CR542229,
AC009292,
AC016355,
U71087,
CH471082,
AC103753,
U25265
Ensembl:
ENSG00000137764
KO:
hsa:5607
|
| Nucleutide sequences |
EMBL-CDS:
CAG47025.1,
AAB16851.1,
AAA96146.1,
AAH08838.1,
AAP35426.1,
BAG56954.1,
AAB16852.2,
EAW77801.1,
EAW77799.1,
EAW77800.1,
EAW77802.1
Gene_ORFName:
hCG_1811971,
hCG_1811971
Ensembl_TRS:
ENST00000395476,
ENST00000178640,
ENST00000354498
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000346493,
ENSP00000378859,
ENSP00000178640
RefSeq:
XP_011520089.1,
NP_660143.1,
NP_002748.1,
XP_024305756.1,
NP_001193733.1,
XP_011520090.1,
XP_016877903.1
|
| Others |
UniRef100:
UniRef100_Q13163,
UniRef100_A0A024R5X5
UniRef90:
UniRef90_Q13163,
UniRef90_Q13163-3
UniRef50:
UniRef50_Q13163
UniGene:
Hs.114198
CCDS:
CCDS10224.1,
CCDS42051.1,
CCDS55970.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员