| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:23:00 | The MKK-Dependent Phosphorylation of p38alpha Is Augmented by Arginine Methylation on Arg49/Arg149 during Erythroid Differentiation. | 32429593 |
| 2020-10-31 13:17:00 | Genome-wide RNA interference screening reveals a COPI-MAP2K3 pathway required for YAP regulation. | 32747557 |
| 2020-08-29 12:46:00 | MKK3 sustains cell proliferation and survival through p38DELTA MAPK activation in colorectal cancer. | 31695024 |
| 2020-04-11 10:09:00 | Expression of human MKK3 in Drosophila is able to initiate JNK-mediated cell migration, cooperates with oncogenic Ras to trigger tumor invasion, and rescue loss-of-lic induced thorax closure defect. | 30770795 |
| 2019-12-28 11:45:00 | it was demonstrated that upregulated miR21 expression and downregulated MKK3 expression suppressed cell proliferation and colony formation, promoted apoptosis, delayed the cell cycle, and inhibited cell migration and invasion. The present findings suggested that miR21 could inhibit the cell growth and metastasis of melanoma by negatively regulating MKK3. | 31257538 |
| Type | IDs |
|---|---|
| Synonymous | MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2 |
| Gene |
UniProtKB-ID:
MP2K3_HUMAN,
Q6FI23_HUMAN
UniprotKB:
P46734,
Q6FI23
UniParc:
UPI000002AE41,
UPI000012F48C,
UPI000002AE42
EMBL:
AB451226,
AB451349,
AK093838,
CR536514,
U66840,
BC032478,
U66839,
AK315505,
D87116,
L36719
Ensembl:
ENSG00000034152
KO:
hsa:5606
|
| Nucleutide sequences |
EMBL-CDS:
BAA13248.1,
AAB40652.1,
AAH32478.1,
BAG52769.1,
AAB40653.1,
AAC41718.1,
BAG70040.1,
CAG38752.1,
BAG37889.1,
BAG70163.1
Ensembl_TRS:
ENST00000361818,
ENST00000342679,
ENST00000316920,
ENST00000613338
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000319139,
ENSP00000478619,
ENSP00000345083,
ENSP00000355081
RefSeq:
XP_011522260.1,
NP_659731.1,
NP_002747.2,
NP_001303261.1,
XP_016880347.1,
XP_016880346.1,
XP_016880348.1,
XP_011522261.1,
XP_005256780.1
|
| Others |
UniRef100:
UniRef100_P46734
UniRef90:
UniRef90_P46734
UniRef50:
UniRef50_P52564
UniGene:
Hs.514012
CCDS:
CCDS11218.1,
CCDS11217.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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