| Type | Description |
|---|---|
| Definition | mesothelin |
| Date | Results | Publications |
|---|---|---|
| 2018-03-03 11:55:00 | our findings show that Sulf-1 is an important tumor suppressor gene in hepatocellular carcinoma (HCC), and its over expression downregulates Msln and results in a decrease in HCC cell proliferation, migration, invasion, and lymphatic metastasis. | 27626699 |
| 2017-09-09 11:53:00 | Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.( | 28287406 |
| 2016-10-22 10:36:00 | Results show that mouse mesothelin is similar to human mesothelin. Its stable overexpression in a pancreatic cancer cell line did not increase cell proliferation, suggesting that mesothelin is not necessarily a tumor progression factor. | 26931187 |
| 2015-04-25 11:51:00 | MSLN has an important role in the growth of lung cancer cells in vivo raising the possibility that inactivation of MPF may be a useful treatment for lung and other MSLN expressing cancers. | 25118887 |
| 2013-08-10 10:04:00 | The mesothelin expression promotes resistance to certain chemotherapy drugs such as TNF-alpha, paclitaxel, and a combination of platinum and cyclophosphamide. | 22721387 |
| Type | IDs |
|---|---|
| Synonymous | MPF |
| Gene |
UniProtKB-ID:
MSLN_MOUSE,
A0A494B9A6_MOUSE
UniprotKB:
Q61468,
A0A494B9A6
UniParc:
UPI0000020C30,
UPI0003D704B3
EMBL:
AC134908,
AK144391,
AK146799,
BC023753,
D86370
Ensembl:
ENSMUSG00000063011
KO:
mmu:56047
|
| Nucleutide sequences |
EMBL-CDS:
BAE25864.1,
AAH23753.1,
BAE27441.1,
BAA13077.1
Ensembl_TRS:
ENSMUST00000237359,
ENSMUST00000238120,
ENSMUST00000236137,
ENSMUST00000075884
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000158357,
ENSMUSP00000158474,
ENSMUSP00000075279,
ENSMUSP00000157558
RefSeq:
NP_061345.1,
NP_001361582.1,
NP_001343215.1
|
| Others |
UniRef100:
UniRef100_Q61468,
UniRef100_A0A494B9A6
UniRef90:
UniRef90_Q61468
UniRef50:
UniRef50_Q13421
UniGene:
Mm.17510
CCDS:
CCDS28526.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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