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56006 SMG9

56006

SMG9

SMG9 nonsense mediated mRNA decay factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition SMG9 nonsense mediated mRNA decay factor

研究结论

Date Results Publications
2021-03-20 13:30:00 Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity. 32469312
2020-09-19 16:25:00 Cryo-EM structure of SMG1-SMG8-SMG9 complex. 31729466
2020-02-29 11:09:00 This study reports the 3.45-A resolution cryo-EM structure of human SMG1-SMG8-SMG9, a phosphatidylinositol-3-kinase (PI(3)K)-related protein kinase (PIKK) complex central to messenger RNA surveillance. 31792449
2019-05-04 10:19:00 These results indicated that miR-4651 regulated Nonsense-mediated mRNA decay by targeting SMG9 mRNA. 30902786
2016-09-03 12:13:00 Mutations in SMG9 cause a multiple congenital anomaly syndrome in humans and mice 27018474

名称对应

Type IDs
Synonymous C19orf61, F17127_1, HBMS
Gene
UniProtKB-ID: SMG9_HUMAN, A0A024R0Q0_HUMAN
UniprotKB: Q9H0W8, A0A024R0Q0
UniParc: UPI0000073356, UPI0000037B1C
EMBL: BC008869, AL136606, CH471126, AC004780, AK022948
Ensembl: ENSG00000105771
KO: hsa:56006
Nucleutide sequences
EMBL-CDS: AAH08869.1, AAC17932.1, CAB66541.1, BAB14323.1, EAW57226.1, EAW57223.1, EAW57224.1
Gene_ORFName: hCG_39354
Ensembl_TRS: ENST00000601170, ENST00000270066
Protein sequencees
Ensembl_PRO: ENSP00000471398, ENSP00000270066
RefSeq: XP_024307376.1, XP_005259114.1, XP_011525417.1, XP_011525416.1, XP_011525415.1, NP_061981.2, XP_011525418.1, XP_016882477.1
Others
UniRef100: UniRef100_Q9H0W8
UniRef90: UniRef90_Q9H0W8
UniRef50: UniRef50_Q9H0W8
UniGene: Hs.466875
CCDS: CCDS33043.2

全选

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