| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase 11 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:04:00 | Circ_0001955 facilitates hepatocellular carcinoma (HCC) tumorigenesis by sponging miR-516a-5p to release TRAF6 and MAPK11. | 31822654 |
| 2020-09-12 16:00:00 | Knocking down of LINC01220 inhibits proliferation and induces apoptosis of endometrial carcinoma through silencing MAPK11. | 31123170 |
| 2020-04-18 11:31:00 | the present results suggested that p38a knockdown impaired migration and proliferation, and increased senescence, in A375 melanoma cells. However, p38b may not be involved in melanoma tumorigenesis. | 31661126 |
| 2018-08-18 10:59:00 | The two kinases HIPK3 and MAPK11 effect on Huntingtin (HTT)levels are mutant HTT protein (mHTT)-dependent, providing a feedback mechanism in which mHTT enhances its own level thus contributing to mHTT accumulation and disease progression. | 29151587 |
| 2017-05-27 11:19:00 | Results provide evidence that p38beta is an unusual enzyme that automodulates its basal, MAPKK-independent activity by several autophosphorylation events, which enhance and suppress its catalytic activity. | 26976637 |
| Type | IDs |
|---|---|
| Synonymous | P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta |
| Gene |
UniProtKB-ID:
MK11_HUMAN
UniprotKB:
Q15759
UniParc:
UPI0001914FDD,
UPI000002AE12
EMBL:
BC027933,
EU332851,
U92268,
AK299745,
AK291845,
AF031135,
JX512451,
Y14440,
CR456514,
DQ279722,
CH471138,
AF001174,
AF001008,
U53442,
AL022328
Ensembl:
ENSG00000185386
KO:
hsa:5600
|
| Nucleutide sequences |
EMBL-CDS:
AAB05036.1,
AAC51250.1,
CAG30400.1,
AAH27933.1,
AAB66313.1,
BAH13116.1,
AAC51373.1,
BAF84534.1,
AGC09598.1,
CAA74792.1,
EAW73524.1,
ABB72677.1,
AAC12714.1,
EAW73526.1,
EAW73525.1,
ABY87540.1
Ensembl_TRS:
ENST00000395764,
ENST00000330651
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379113,
ENSP00000333685
RefSeq:
NP_002742.3
|
| Others |
UniRef100:
UniRef100_Q15759
UniRef90:
UniRef90_Q15759
UniRef50:
UniRef50_Q15759
UniGene:
Hs.57732
CCDS:
CCDS14090.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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