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55997 CFC1

55997

CFC1

cripto, FRL-1, cryptic family 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition cripto, FRL-1, cryptic family 1

研究结论

Date Results Publications
2018-05-19 11:54:00 The knockdown and overexpression of CFC1 were performed using a lentiviral system in NB cell lines. The overexpression of CFC1 increased sphere formation, cell growth, and colony formation. 28620148
2017-09-09 13:43:00 Results demonstrated that over expression of Snail suppresses Cryptic expression and confirmed that Snail directly binds to Cryptic gene promoter and regulates its expression. 27793090
2016-11-12 10:29:00 enhances macrophage phagocytic activity and upregulates the production of anti- and pro-inflammatory cytokines via the NF-kappaB signaling pathway 26476731
2015-04-25 11:33:00 Data indicate that the duplication and deletion of CFC1 protein may play key roles in the occurrence of heterotaxy syndrome. 25423076
2011-11-19 10:58:00 CFC1 may be involved in the etiology of non-syndromic congenital heart disease in a Chinese population. 19853937

名称对应

Type IDs
Synonymous CFC1B, CRYPTIC, DTGA2, HTX2
Gene
UniProtKB-ID: CFC1_HUMAN, A0A087WX98_HUMAN, A0A087WWV2_HUMAN
UniprotKB: P0CG37, A0A087WX98, A0A087WWV2
UniParc: UPI00026C242D, UPI0000070FF1, UPI00026C242E
EMBL: BC074825, AF312769, BC146897, BC069508, AC140481, BC110080, BC074826, AF312925, AK315326
Ensembl: ENSG00000136698
KO: hsa:55997
Nucleutide sequences
EMBL-CDS: AAG30294.1, AAH74825.1, BAG37727.1, AAH69508.1, AAH74826.1, AAG42475.1, AAI10081.1, AAI46898.1
Ensembl_TRS: ENST00000259216, ENST00000621673, ENST00000615342
Protein sequencees
Ensembl_PRO: ENSP00000259216, ENSP00000480843, ENSP00000480526
RefSeq: NP_115934.1, NP_001257349.1, XP_011509788.1, NP_001257350.1
Others
UniRef100: UniRef100_A0A087WX98, UniRef100_A0A087WWV2, UniRef100_P0CG37
UniRef90: UniRef90_P0CG37, UniRef90_A0A2I3H4U1, UniRef90_A0A087WWV2
UniRef50: UniRef50_P0CG37, UniRef50_A0A087WWV2
UniGene: Hs.567542
CCDS: CCDS2162.1

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