Camkk1 - calcium/calmodulin-dependent protein kinase kinase 1, alpha-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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55984 Camkk1

基因描述

Type	Description
Definition	calcium/calmodulin-dependent protein kinase kinase 1, alpha

研究结论

Date	Results	Publications
2016-10-22 11:58:00	the CaMKK-CaMKIalpha cascade is required for the axonal growth effect of Wnt5a during neuronal polarization.	26772170
2014-12-20 12:04:00	Data (including data from knockout mice) suggest that up-regulation of Camkk1 and calcium signaling stimulates muscle growth via up-regulation of mTORC1 (mammalian target of rapamycin complex 1) signaling and muscle protein biosynthesis.	25159322
2014-03-01 10:02:00	caCaMKKalpha stimulates glucose uptake additively with insulin, and in insulin-resistant muscle, and alters the phosphorylation of TBC1D1/TBC1D4.	24101676
2010-01-21 00:00:00	ERK activation and neurite outgrowth in response to depolarization are mediated by CaMKK activation of CaMKI	15150258
2010-01-21 00:00:00	Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways	19520843

名称对应

Type	IDs
Synonymous	AI846603, CaMKKalpha, Camkk, caM-KK 1, caM-KK alpha, caMKK 1, caMKK alpha
Gene	UniProtKB-ID: KKCC1_MOUSE UniprotKB: Q8VBY2 UniParc: UPI00000E638D EMBL: BC017529, AF461705, AF461702, AF461706, AF461704, AF117384, AF461703 Ensembl: ENSMUSG00000020785 KO: mmu:55984
Nucleutide sequences	EMBL-CDS: AAL67849.1, AAF08348.1, AAH17529.1 Ensembl_TRS: ENSMUST00000092937
Protein sequencees	Ensembl_PRO: ENSMUSP00000090613 RefSeq: NP_001349770.1, NP_061371.2, XP_006533824.1
Others	UniRef100: UniRef100_Q8VBY2 UniRef90: UniRef90_Q8VBY2 UniRef50: UniRef50_Q96RR4 UniGene: Mm.9998 CCDS: CCDS24993.1

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
32325033	BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili	2020-04-22	-
26772170	Facilitation of axon outgrowth via a Wnt5a-CaMKK-CaMKIÎ± pathway during neuronal polarization. Mol Brain Shin-ichiro Horigane , Natsumi Ageta-Ishihara , Satoshi Kamijo , Hajime Fujii , Michiko Okamura , Makoto Kinoshita , Sayaka Takemoto-Kimura , Haruhiko Bito	2016-01-01	-
25159322	Constitutive activation of CaMKKÎ± signaling is sufficient but not necessary for mTORC1 activation and growth in mouse skeletal muscle. Am. J. Physiol. Endocrinol. Metab. Jeremie L A Ferey , Jeffrey J Brault , Cheryl A S Smith , Carol A Witczak	2014-10-15	-
24101676	Constitutively active CaMKKÎ± stimulates skeletal muscle glucose uptake in insulin-resistant mice in vivo. Diabetes J Matthew Hinkley , Jeremie L Ferey , Jeffrey J Brault , Cheryl A S Smith , Laura A A Gilliam , Carol A Witczak	2014-01-01	-
22334678	Calcium/calmodulin-dependent protein kinase kinase 2 regulates macrophage-mediated inflammatory responses. J Biol Chem Luigi Racioppi , Pamela K Noeldner , Fumin Lin , Stephanie Arvai , Anthony R Means	2012-03-30	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21558011	Forebrain-specific constitutively active CaMKKÎ± transgenic mice show deficits in hippocampus-dependent long-term memory. Neurobiol Learn Mem Taku Kaitsuka , Sheng-Tian Li , Kenji Nakamura , Keizo Takao , Tsuyoshi Miyakawa , Masayuki Matsushita	2011-09-01	Camkk1
20798045	Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Proc Natl Acad Sci U S A JoÃ£o D Pereira , Stephen N Sansom , James Smith , Marc-Werner Dobenecker , Alexander Tarakhovsky , Frederick J Livesey	2010-09-07	-
19776387	The presence and activation of two essential transcription factors (cAMP response element-binding protein and cAMP-dependent transcription factor ATF1) in the two-cell mouse embryo. Biol. Reprod. X L Jin , C O'Neill	2010-02-01	Camk2d, Atf1, Camk2a, Camk2b, Camk2g, Camk4, Creb1, Camkk2, Camk1, Camkk1
19864584	Control of cortical axon elongation by a GABA-driven Ca2+/calmodulin-dependent protein kinase cascade. J Neurosci Natsumi Ageta-Ishihara , Sayaka Takemoto-Kimura , Mio Nonaka , Aki Adachi-Morishima , Kanzo Suzuki , Satoshi Kamijo , Hajime Fujii , Tatsuo Mano , Frank Blaeser , Talal A Chatila , Hidenobu Mizuno , Tomoo Hirano , Yoshiaki Tagawa , Hiroyuki Okuno , Haruhiko Bito	2009-10-28	-

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