| Type | Description |
|---|---|
| Definition | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) |
| Date | Results | Publications |
|---|---|---|
| 2017-12-16 10:59:00 | Agpat1-/- mice developed widespread disturbances of metabolism, sperm development, and neurologic function resulting from disrupted phospholipid homeostasis. AGPAT1 appears to serve important functions in the physiology of multiple organ systems. The Agpat1-deficient mouse provides an important model in which to study the contribution of phospholipid and triacylglycerol synthesis to physiology and diseases. | 28973305 |
| 2011-01-22 10:39:00 | observations strongly implicate AGPAT1 in the development of skeletal muscle, specifically to terminal differentiation. These findings are linked to the regulation of actin cytoskeleton | 20561744 |
| 2010-01-21 00:00:00 | mtGPAT1 might serve as a novel target for treatment of hepatic steatosis and hepatic insulin resistance and that long chain acyl-CoA's do not mediate fat-induced hepatic insulin resistance in this model. | 16054099 |
| 2010-01-21 00:00:00 | mAGPAT 1, 2, and 3 mRNA levels increased rapidly in mouse skin after acute permeability barrier disruption | 16150824 |
| Type | IDs |
|---|---|
| Synonymous | 1-AGP, 1-AGPAT, AW047140 |
| Gene |
UniProtKB-ID:
PLCA_MOUSE,
A0A0R4J263_MOUSE
UniprotKB:
O35083,
A0A0R4J263
UniParc:
UPI000002437D,
UPI000002913D
EMBL:
AB005623,
AF030001,
CT009767
Ensembl:
ENSMUSG00000034254
KO:
mmu:55979
|
| Nucleutide sequences |
EMBL-CDS:
BAA22599.1,
AAB82009.1
Ensembl_TRS:
ENSMUST00000114140,
ENSMUST00000037489,
ENSMUST00000174595
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000048573,
ENSMUSP00000134358,
ENSMUSP00000109776
RefSeq:
XP_006524711.1,
NP_001156851.1,
XP_030105775.1,
NP_061350.3,
XP_006524710.1
|
| Others |
UniRef100:
UniRef100_O35083,
UniRef100_A0A0R4J263
UniRef90:
UniRef90_O35083
UniRef50:
UniRef50_Q99943
UniGene:
Mm.8684
CCDS:
CCDS37590.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
| 28973305 |
Metabolic, Reproductive, and Neurologic Abnormalities in Agpat1-Null Mice. Endocrinology Anil K Agarwal , Katie Tunison , Jasbir S Dalal , Sneha S Nagamma , F Kent Hamra , Shireesha Sankella , Xinli Shao , Richard J Auchus , Abhimanyu Garg |
2017-11-01 | - |
| 28378742 |
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Sci Rep Tingting Zhang , Wei Du , Andrew F Wilson , Satoshi H Namekawa , Paul R Andreassen , Amom Ruhikanta Meetei , Qishen Pang |
2017-04-05 | - |
| 27113764 |
The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase. EMBO Rep Beezly S Groh , Feng Yan , Matthew D Smith , Yanbao Yu , Xian Chen , Yue Xiong |
2016-05-01 | - |
| 24194600 |
Nucleic Acids Res. Gautier Koscielny , Gagarine Yaikhom , Vivek Iyer , Terrence F Meehan , Hugh Morgan , Julian Atienza-Herrero , Andrew Blake , Chao-Kung Chen , Richard Easty , Armida Di Fenza , Tanja Fiegel , Mark Grifiths , Alan Horne , Natasha A Karp , Natalja Kurbatova , Jeremy C Mason , Peter Matthews , Darren J Oakley , Asfand Qazi , Jack Regnart , Ahmad Retha , Luis A Santos , Duncan J Sneddon , Jonathan Warren , Henrik Westerberg , Robert J Wilson , David G Melvin , Damian Smedley , Steve D M Brown , Paul Flicek , William C Skarnes , Ann-Marie Mallon , Helen Parkinson |
2014-01-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20561744 |
A role for 1-acylglycerol-3-phosphate-O-acyltransferase-1 in myoblast differentiation. Differentiation Angela R Subauste , Brandon Elliott , Arun K Das , Charles F Burant |
2010-06-19 |
Agpat1
|
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 18973680 |
BMC Genomics Owen J Tamplin , Doris Kinzel , Brian J Cox , Christine E Bell , Janet Rossant , Heiko Lickert |
2008-01-01 |
Rnaset2a,
Ildr2,
2810410L24Rik,
Pifo,
Trrap,
Plekha1,
Cd276,
Phldb1,
6330403K07Rik,
Txndc5,
Unc119b,
Otub1,
Napg,
Cald1,
Pygb,
Pygl,
Hspa13,
Rpl31,
Acvr2b,
Agtrap,
Ank3,
Anxa5,
Ap4s1,
App,
Arg1,
Astn1,
Atm,
Bcl2l2,
Fabp7,
Hyou1,
Pdia4,
Cbx3,
Cd24a,
Cd59a,
Cdkn1c,
Cdx1,
Cldn4,
Cnn2,
Col1a1,
Hapln1,
Csnk2a1,
Cyb561,
Cyp51,
Dbt,
Mapre1,
Esd,
Amz2,
Colec12,
Fgfr2,
Fjx1,
Foxd4,
Flt4,
Fstl1,
Gal,
Galnt1,
Galt,
Gas5,
Nr6a1,
Gna14,
Gng10,
Gpc3,
Lpar1,
Gpx2,
Gsta4,
Gstm5,
Hdgf,
Hmgb1,
Foxa1,
Foxa2,
Hnrnpab,
Hoxa1,
Hpn,
Prmt1,
Sdc2,
Igfbp3,
Igfbp5,
Inpp1,
Itch,
Itga3,
Stt3a,
Khsrp,
Mxd3,
Cd99l2,
Mfap2,
Mdk,
Meis1,
Mest,
Kitl,
Mlf1,
Mvk,
Myef2,
Myl4,
Myl7,
Myl1,
Nnat,
Pabpc1,
Pak1,
Pcolce,
Pcsk5
|
| 17967808 |
EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic Roland H Friedel , Claudia Seisenberger , Cornelia Kaloff , Wolfgang Wurst |
2007-09-01 |
Gm11696,
Gm10589,
Apela,
Gm10822,
Gm2085,
Gm2312,
Lncenc1,
Gm2381,
Gm2659,
Gm2679,
Dynlt1c,
Gm3134,
Gm3143,
Gm3236,
Gm3574,
Gm3581,
Gm3718,
Gm3859,
Gm3905,
Gm3952,
Gm3957,
Gm3973,
Gm12057,
Rex2,
Gm4218,
Gm4225,
Gm16476,
Gm4407,
Gm14410,
Gm4420,
Gm14005,
1300002E11Rik,
Gm4532,
Srcap,
Gm17789,
Gm10751,
Gm14321,
0610009E02Rik,
Gm12758,
Gm11532,
Phactr4,
Rusc2,
AK010878,
Gm10778,
5830417I10Rik,
Mir1902,
Gm15270,
Gm11767,
Ino80dos,
Bsdc1,
Gm7645,
Gm20590,
Slc44a1,
Gm15545,
Gm17292,
2900009J06Rik,
Kifc1,
Gm13150,
Gm19426,
Gm19428,
Gm19474,
Gm14963,
Gm19565,
Gm19592,
Gm12588,
Snhg4,
Gm19702,
Gm19705,
Platr22,
Nuggc,
Zfp534,
Gm19860,
Gm11725,
Gm19876,
Gm19889,
Gm16201,
Gm13056,
Tnfsf13os,
Gm19925,
Gm19976,
Gm20014,
Gm16740,
Gm20039,
Gm20045,
AU020206,
Ccdc170,
Trp53cor1,
Gm20266,
Gm20324,
Zfp518b,
Gm14401,
AI480526,
Pds5b,
Ube3c,
Gm21297,
Akap9,
Gm29724,
Itfg2,
Parp11
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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