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55971 BAIAP2L1

55971

BAIAP2L1

BAI1 associated protein 2 like 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition BAI1 associated protein 2 like 1

研究结论

Date Results Publications
2019-11-02 11:06:00 IRTKS localizes to the distal tips of actively growing microvilli via a mechanism that requires its N-terminal I-BAR domain. At microvillar tips, IRTKS promotes elongation through a mechanism involving its C-terminal actin-binding WH2 domain. 30197089
2017-08-05 10:12:00 Rho family GTPases use the I-BAR proteins, IRSp53 (also known as BAIAP2), IRTKS and Pinkbar, as a central mechanism to modulate cell morphology. 27278019
2017-06-03 10:20:00 IRTKS promoted serum-induced cell migration along with enhanced phosphorylation of mitogen activated kinases Erk1/2 and p38, and activation of small GTPases Rac1 and Cdc42. In addition, cells overexpressing IRTKS exhibited an increased polarity characterized by elongated cytoplasm and extensive lamellipodia at leading edges. 27693783
2016-05-07 10:18:00 Upregulation of BAIAP2L1 is associated with ovarian cancer. 26222696
2016-03-19 10:24:00 Lacking the Bin-Amphiphysin-Rvs (BAR) dimerization domain of BAIAP2L1. 25589496

名称对应

Type IDs
Synonymous IRTKS
Gene
UniProtKB-ID: BI2L1_HUMAN
UniprotKB: Q9UHR4
UniParc: UPI0000035DA9
EMBL: CH236956, AK027142, AC093169, AC093799, AC004841, CH471091, AF119666, BC013888
Ensembl: ENSG00000006453
KO: hsa:55971
Nucleutide sequences
EMBL-CDS: AAD20937.1, AAS07550.1, BAB15671.1, AAS07549.1, EAW76706.1, AAH13888.1, AAF17223.2, EAL23890.1
Ensembl_TRS: ENST00000005260
Protein sequencees
Ensembl_PRO: ENSP00000005260
RefSeq: NP_061330.2
Others
UniRef100: UniRef100_Q9UHR4
UniRef90: UniRef90_Q9UHR4
UniRef50: UniRef50_Q9UHR4
UniGene: Hs.656063
CCDS: CCDS34687.1

全选

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