| Type | Description |
|---|---|
| Definition | BAI1 associated protein 2 like 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 11:06:00 | IRTKS localizes to the distal tips of actively growing microvilli via a mechanism that requires its N-terminal I-BAR domain. At microvillar tips, IRTKS promotes elongation through a mechanism involving its C-terminal actin-binding WH2 domain. | 30197089 |
| 2017-08-05 10:12:00 | Rho family GTPases use the I-BAR proteins, IRSp53 (also known as BAIAP2), IRTKS and Pinkbar, as a central mechanism to modulate cell morphology. | 27278019 |
| 2017-06-03 10:20:00 | IRTKS promoted serum-induced cell migration along with enhanced phosphorylation of mitogen activated kinases Erk1/2 and p38, and activation of small GTPases Rac1 and Cdc42. In addition, cells overexpressing IRTKS exhibited an increased polarity characterized by elongated cytoplasm and extensive lamellipodia at leading edges. | 27693783 |
| 2016-05-07 10:18:00 | Upregulation of BAIAP2L1 is associated with ovarian cancer. | 26222696 |
| 2016-03-19 10:24:00 | Lacking the Bin-Amphiphysin-Rvs (BAR) dimerization domain of BAIAP2L1. | 25589496 |
| Type | IDs |
|---|---|
| Synonymous | IRTKS |
| Gene |
UniProtKB-ID:
BI2L1_HUMAN
UniprotKB:
Q9UHR4
UniParc:
UPI0000035DA9
EMBL:
CH236956,
AK027142,
AC093169,
AC093799,
AC004841,
CH471091,
AF119666,
BC013888
Ensembl:
ENSG00000006453
KO:
hsa:55971
|
| Nucleutide sequences |
EMBL-CDS:
AAD20937.1,
AAS07550.1,
BAB15671.1,
AAS07549.1,
EAW76706.1,
AAH13888.1,
AAF17223.2,
EAL23890.1
Ensembl_TRS:
ENST00000005260
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000005260
RefSeq:
NP_061330.2
|
| Others |
UniRef100:
UniRef100_Q9UHR4
UniRef90:
UniRef90_Q9UHR4
UniRef50:
UniRef50_Q9UHR4
UniGene:
Hs.656063
CCDS:
CCDS34687.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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