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55963 Slc1a4

55963

Slc1a4

solute carrier family 1 (glutamate/neutral amino acid transporter), member 4

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 1 (glutamate/neutral amino acid transporter), member 4

研究结论

Date Results Publications
2019-10-12 10:04:00 The ability of L-4FPG to penetrate the brain makes this compound a useful tool to further evaluate the function of ASCT1 and ASCT2 transporters in the CNS. 30171039
2018-10-13 12:01:00 ASCT1, rather than ASCT2, is a component of the brain serine shuttle. ASCT1-KO mice display motor and neurodevelopmental deficits reminiscent of ASCT1 missense mutations in humans. 30185558
2010-01-21 00:00:00 Results demonstrate injury-induced changes in Phgdh and ASCT1 expression. 18751891
2010-01-21 00:00:00 results strongly suggest that combinations of amino acid sequence changes and N-linked oligosaccharides in a critical carboxyl-terminal region of extracellular loop 2 (ECL2) control retroviral utilization of both the ASCT1 and ASCT2 receptors 12584318
2010-01-21 00:00:00 either Phgdh or ASCT1 is provided to each segment of renal tubules, suggesting that metabolic interplay mediated by L-serine biosynthesis and supply may exist in the kidney 17510490

名称对应

Type IDs
Synonymous ASCT-1, ASCT1, AW045657, SATT
Gene
UniProtKB-ID: SATT_MOUSE, Q3US35_MOUSE, Q3UTP8_MOUSE
UniprotKB: O35874, Q3US35, Q3UTP8
UniParc: UPI0000020E02, UPI00005AC004
EMBL: AK139248, AK136900, BC052733, U75215, AK140866
Ensembl: ENSMUSG00000020142
KO: mmu:55963
Nucleutide sequences
EMBL-CDS: AAB71740.1, AAH52733.1, BAE24502.1, BAE23932.1, BAE23162.1
Ensembl_TRS: ENSMUST00000109594
Protein sequencees
Ensembl_PRO: ENSMUSP00000105223
RefSeq: NP_061349.3
Others
UniRef100: UniRef100_O35874, UniRef100_Q3US35
UniRef90: UniRef90_O35874
UniRef50: UniRef50_O35874
UniGene: Mm.6379
CCDS: CCDS24457.1

全选

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