| Type | Description |
|---|---|
| Definition | protein kinase cGMP-dependent 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:24:00 | Expression of PKG2 in ovarian cancer and its effect on epidermal growth factor receptor. | 32521860 |
| 2020-06-06 10:15:00 | These findings suggested a PKG II-specific phosphorylation site on EGFR. | 31395339 |
| 2018-08-18 10:13:00 | L-Arginine is a potential alternative to PKG II activation. | 29401205 |
| 2018-05-12 11:37:00 | Comparative analysis of the backbone hydrogen/deuterium exchange patterns in PKG II:8-pCPT-cGMP and previously reported PKG Ibeta:cGMP XN structures suggests that the ability of these agonists to activate PKG is related to how effectively they quench dynamics of the cyclic nucleotide binding pocket and the surrounding regions. | 29517905 |
| 2018-01-27 11:33:00 | the results indicated that PKG II could block c-Met activation via phosphorylating Ser985 | 27147579 |
| Type | IDs |
|---|---|
| Synonymous | PKG2, PRKGR2, cGK2, cGKII |
| Gene |
UniProtKB-ID:
KGP2_HUMAN,
B4DLF9_HUMAN,
A0A140VJM3_HUMAN,
B7ZA25_HUMAN
UniprotKB:
Q13237,
B4DLF9,
A0A140VJM3,
B7ZA25
UniParc:
UPI000012DDC6,
UPI0001915442,
UPI00017A750D,
UPI0001AE744C
EMBL:
Y16114,
Y16112,
Y16117,
AK316140,
Y16109,
AK296979,
D70899,
Y16118,
AC139722,
Y16121,
Y16115,
AC098819,
Y16107,
Y16123,
Y16116,
Y16108,
Y16120,
Y16119,
Y16113,
Y16122,
KF457787,
Y16110,
X94612,
CH471057,
HM005412,
AK297673,
Y16111,
Y16106
Ensembl:
ENSG00000138669
KO:
hsa:5593
|
| Nucleutide sequences |
EMBL-CDS:
BAG60035.1,
CAA64318.1,
BAA18934.1,
CAA76073.1,
BAG59521.1,
EAX05867.1,
AEE61010.1,
BAH14511.1
Gene_ORFName:
hCG_25079
Ensembl_TRS:
ENST00000264399,
ENST00000628926,
ENST00000395578,
ENST00000545647
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000486129,
ENSP00000378945,
ENSP00000264399,
ENSP00000439967
RefSeq:
NP_001269409.1,
NP_001269411.1,
XP_016863906.1,
XP_016863904.1,
XP_016863907.1,
XP_016863902.1,
NP_001350330.1,
NP_001269410.1,
NP_006250.1,
NP_001269414.1,
XP_016863905.1,
NP_001269412.1,
XP_016863903.1
|
| Others |
UniRef100:
UniRef100_Q13237,
UniRef100_B4DLF9
UniRef90:
UniRef90_Q13237,
UniRef90_B4DLF9
UniRef50:
UniRef50_Q13237,
UniRef50_A0A6J2R4X6
UniGene:
Hs.570833
CCDS:
CCDS64005.1,
CCDS3589.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员