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55929 DMAP1

55929

DMAP1

DNA methyltransferase 1 associated protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition DNA methyltransferase 1 associated protein 1

研究结论

Date Results Publications
2019-06-08 12:43:00 Findings reveal a regulatory role of Bub3 in DMAP1-mediated DNA methylation upon mitotic stress. 30553276
2017-06-24 10:31:00 A novel tumour suppressor gene, MDGA2, which is frequently inactivated by promoter methylation in Gastric cancer, exerts a tumour suppressive function by cooperating with DMAP1 to activate the p53/p21 signalling cascade. 26206665
2015-01-03 11:46:00 Targeted knockdown of human DNA methyltransferase 1 expression restores the expression levels of tumor suppressor genes, thus inhibiting the proliferation of cholangiocarcinoma cell line cells. 24361215
2014-03-15 10:53:00 These results suggest that DMAP1 is a critical regulator of ATM activity and function 23318425
2011-12-03 11:30:00 positive staining for DNMT1 in clinical cancer specimens was significantly linked to lower rates of response to treatments and shorter survival of patients with pharyngeal cancer. 21284050

名称对应

Type IDs
Synonymous DNMAP1, DNMTAP1, EAF2, MEAF2, SWC4
Gene
UniProtKB-ID: DMAP1_HUMAN
UniprotKB: Q9NPF5
UniParc: UPI00001294C6
EMBL: AL137200, BC002855, CH471059, AB037846, AL136657, AK289366, BX537895, AF265228, AL035417, BC008053, AK021605, AM393614
Ensembl: ENSG00000178028
KO: hsa:55929
Nucleutide sequences
EMBL-CDS: BAA92663.1, AAH08053.1, BAB13854.1, BAF82055.1, CAL38490.1, EAX07048.1, EAX07047.1, EAX07046.1, CAD97886.1, CAB66592.1, AAF87079.1, EAX07051.1, CAB69910.1, AAH02855.1
Ensembl_TRS: ENST00000361745, ENST00000315913, ENST00000372289
Protein sequencees
Ensembl_PRO: ENSP00000354697, ENSP00000312697, ENSP00000361363
RefSeq: NP_001029195.1, NP_061973.1, NP_001029196.1
Others
UniRef100: UniRef100_Q9NPF5
UniRef90: UniRef90_Q9NPF5
UniRef50: UniRef50_Q9NPF5
UniGene: Hs.8008
CCDS: CCDS509.1

全选

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