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55922 NKRF

55922

NKRF

NFKB repressing factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition NFKB repressing factor

研究结论

Date Results Publications
2020-07-25 11:45:00 Low NRF expression is associated with obesity induced nephropathy. 30729676
2020-07-18 10:40:00 RNA affinity, helicase, and ATPase activity of DHX15 are increased when the G-patch motif of NKRF binds in an extended conformation across the helicase surface 32179686
2018-04-28 12:02:00 NKRF is a nucleolar HSP essential for nucleolus homeostasis and cell survival under proteotoxic stress. NKRF is a thermosensor translocating from the nucleolus to the nucleoplasm during heat stress; nucleolar pools are replenished upon HSF1-mediated NKRF resynthesis. NKRF is an unconventional HSP crucial for correct rRNA processing. Under stress conditions, NKRF directs XRN2 nucleolus/nucleoplasm trafficking. 28096332
2018-01-13 12:44:00 Data suggest that L protein from LCMV interactions with host proteome, specifically DDX3X, NKRF, and TRIM21. (LCMV = Lymphocytic choriomeningitis mammarenavirus; DDX3X = DEAD-box helicase 3; NKRF = NF-kappa-B-repressing factor; TRIM21 = tripartite motif-containing protein-21) 29261807
2017-09-23 11:38:00 depletion of NKRF, XRN2 or DHX15 impairs an early pre-rRNA cleavage step. 28115624

名称对应

Type IDs
Synonymous ITBA4, NRF
Gene
UniProtKB-ID: NKRF_HUMAN, A3F769_HUMAN
UniprotKB: O15226, A3F769
UniParc: UPI0000211E22, UPI00001BBB5F
EMBL: AJ011812, BC040379, AL539002, EF216689, BC047878, Y07707, CH471161, AY208891, AC004913
Ensembl: ENSG00000186416
KO: hsa:55922
Nucleutide sequences
EMBL-CDS: CAB56459.1, AAH47878.1, EAW89859.1, AAP43025.1, AAH40379.1, CAA68976.1, ABN11235.1, EAW89860.1
Gene_ORFName: hCG_23185
Ensembl_TRS: ENST00000542113, ENST00000371527, ENST00000304449
Protein sequencees
Ensembl_PRO: ENSP00000442308, ENSP00000304803, ENSP00000360582
RefSeq: NP_060014.3
Others
UniRef100: UniRef100_O15226
UniRef90: UniRef90_O15226
UniRef50: UniRef50_O15226
UniGene: Hs.437084

全选

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