| Type | Description |
|---|---|
| Definition | protein kinase cGMP-dependent 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:16:00 | Expression profiles of PRKG1, SDF2L1 and PPP1R12A are predictive and prognostic factors for therapy response and survival in high-grade serous ovarian cancer. | 32096871 |
| 2021-01-16 15:54:00 | A substitution in cGMP-dependent protein kinase 1 associated with aortic disease induces an active conformation in the absence of cGMP. | 32506052 |
| 2020-04-25 11:34:00 | O-GlcNAcylation activates PGK1 activity to enhance lactate production, and simultaneously induces PGK1 translocation into mitochondria. | 31911580 |
| 2020-04-11 12:29:00 | Increased oxidation of PKGIalpha to its disulfide-activated state found in pulmonary arteries from mice with hypoxic pulmonary arterial hypertension (PH) or lungs from patients. It caused by chronic hypoxia, and it limits progression of PH by pulmonary vasodilation that counters and offsets maladaptive vasoconstriction, and also disulfide PKGIalpha is protective by preventing maladaptive growth and fibrosis signaling. | 31186362 |
| 2020-03-21 11:18:00 | Self-regulation and the foraging gene (PRKG1) in humans. | 30782798 |
| Type | IDs |
|---|---|
| Synonymous | AAT8, PKG, PKG1, PRKG1B, PRKGR1B, cGK, cGK 1, cGK1, cGKI, cGKI-BETA, cGKI-alpha |
| Gene |
UniProtKB-ID:
KGP1_HUMAN
UniprotKB:
Q13976
UniParc:
UPI00004042B8,
UPI000016A69C,
UPI000012DDCD
EMBL:
AK093436,
BC062688,
Z92878,
AC027118,
AC009986,
CH471083,
AL391378,
Z92870,
Z92875,
AC068062,
Y07512,
Z92868,
D45864,
AC026228,
AL607031,
AC022025,
Z92873,
Z92880,
EF560730,
Z92867,
Z92877,
Z92882,
AC069079,
Z92885,
Z92869,
Z92872,
AL157399,
Z92876,
AC073584,
AL731537,
Z92883,
AC022537,
Z92884,
Z92871,
Z92874,
AL596105,
Z92879,
Z92881,
BC127090,
AL928686
Ensembl:
ENSG00000185532
KO:
hsa:5592
|
| Nucleutide sequences |
EMBL-CDS:
CAI39626.1,
AAI27091.1,
CAI41305.1,
EAW54140.1,
CAI40743.1,
BAA08297.1,
CAA68810.1,
CAI17115.1,
BAG52715.1,
AAH62688.1,
CAB07436.1,
CAB07437.1,
ABQ59040.1
Ensembl_TRS:
ENST00000373980,
ENST00000401604
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000384200,
ENSP00000363092
RefSeq:
XP_016871901.1,
XP_011538254.1,
NP_001361710.1,
NP_006249.1,
NP_001091982.1,
XP_016871902.1,
NP_001361711.1
|
| Others |
UniRef100:
UniRef100_Q13976
UniRef90:
UniRef90_Q13976
UniRef50:
UniRef50_Q13976
UniGene:
Hs.407535
CCDS:
CCDS44399.1,
CCDS7244.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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