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55915 LANCL2

55915

LANCL2

LanC like 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition LanC like 2

研究结论

Date Results Publications
2020-12-12 13:22:00 Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle. 32591558
2019-01-19 12:31:00 Site-directed mutagenesis (single mutant R118I, triple mutants R118I/R22I/K362I and R118I/S41A/E46I) and equilibrium binding experiments on the mutated LANCL2 proteins identified a high-affinity ABA-binding site involving R118, with a KD of 2.6nM+/-1.2nM, as determined by surface plasmon resonance. 29421190
2018-04-07 10:16:00 human LANCL2 is a non-transmembrane G protein-coupled receptor susceptible to hormone-induced nuclear translocation. 27222287
2015-08-01 11:01:00 Data indicate that lanthionine synthetase C-like 2 (LanCL2) depletion sensitizes cells to apoptosis through down-regulating serine/threonine protein kinase Akt phosphorylation. 25273559
2012-01-21 10:18:00 human recombinant LANCL2 binds abscisic acid (ABA) directly and provide the first demonstration of ABA binding to a mammalian ABA receptor. 22037458

名称对应

Type IDs
Synonymous GPR69B, TASP
Gene
UniProtKB-ID: LANC2_HUMAN, B3KTN5_HUMAN
UniprotKB: Q9NS86, B3KTN5
UniParc: UPI000006F7D0, UPI0000372E49
EMBL: AL713665, AK313326, AB035966, AC073347, CH236957, AK095857, BC004887, CH471201, BC070049, AF353942, AJ278245
Ensembl: ENSG00000132434
KO: hsa:55915
Nucleutide sequences
EMBL-CDS: EAL23810.1, AAH04887.2, BAA96800.1, AAQ93360.1, CAD28471.1, EAW50968.1, AAH70049.1, CAC21715.1, BAG36131.1, AAK83286.1, BAG53147.1
Ensembl_TRS: ENST00000254770
Protein sequencees
Ensembl_PRO: ENSP00000254770
RefSeq: NP_061167.1
Others
UniRef100: UniRef100_B3KTN5, UniRef100_Q9NS86
UniRef90: UniRef90_Q9NS86
UniRef50: UniRef50_Q9NS86
UniGene: Hs.595384, Hs.706612
CCDS: CCDS5517.1

全选

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