| Type | Description |
|---|---|
| Definition | erbb2 interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 11:52:00 | Findings show that ERBIN is required for Dsg1 requires to downregulate EGFR/Erk signaling and fully suppress invadopodia formation. | 30655320 |
| 2020-03-21 11:04:00 | Erbin is mainly localized in endothelial cells in human umbilical veins and plays a critical role in endothelial cell migration and tubular formation via the Smad1/5 pathway. | 30367512 |
| 2019-09-21 10:54:00 | Erbin interacted with kinase suppressor of Ras 1 (KSR1) and displaced it from the RAF/MEK/ERK complex to prevent signal propagation..These findings establish the scaffold protein Erbin as a negative regulator of EMT and tumorigenesis in colorectal cancer through direct suppression of Akt and RAS/RAF signaling | 29980571 |
| 2019-03-30 10:07:00 | Erbb2 interacting protein (ERBB2IP), a known target of miR-23c, was positively regulated by KTN1-AS1. | 30551364 |
| 2019-01-19 11:44:00 | miR-23c inhibited cell proliferation and accelerated apoptosis by attenuating ERBB2IP. | 30103114 |
| Type | IDs |
|---|---|
| Synonymous | ERBB2IP, HEL-S-78, LAP2 |
| Gene |
UniProtKB-ID:
ERBIN_HUMAN
UniprotKB:
Q96RT1
UniParc:
UPI0000043C3D,
UPI0000D61631,
UPI0001D3B313,
UPI0000E44560,
UPI000020C83D,
UPI0001D3B314,
UPI0000D61632,
UPI000013C941,
UPI0000E4455F
EMBL:
AC010359,
AB033051,
AF263744,
AK001180,
BC126464,
BC115012,
AK304693,
BC144075,
AF276423,
BC050692,
AC025442
Ensembl:
ENSG00000112851
KO:
hsa:55914
|
| Nucleutide sequences |
EMBL-CDS:
BAG65463.1,
AAK69431.1,
AAI15013.1,
AAI26465.1,
AAF77048.1,
BAA91538.1,
AAI44076.1,
AAH50692.1,
BAA86539.2
Ensembl_TRS:
ENST00000508515,
ENST00000380938,
ENST00000380935,
ENST00000284037,
ENST00000506030,
ENST00000380943,
ENST00000511297
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000370325,
ENSP00000370330,
ENSP00000426632,
ENSP00000422015,
ENSP00000422766,
ENSP00000370322,
ENSP00000284037
RefSeq:
NP_061165.1,
XP_006714723.1,
XP_016865126.1,
XP_005248612.1,
XP_005248611.1,
XP_016865124.1,
NP_001240630.1,
NP_001240626.1,
NP_001240627.1,
NP_001006600.1,
NP_001240628.1,
XP_016865125.1
|
| Others |
UniRef100:
UniRef100_Q96RT1
UniRef90:
UniRef90_Q96RT1
UniRef50:
UniRef50_Q96RT1
UniGene:
Hs.591774,
Hs.597241
CCDS:
CCDS58952.1,
CCDS58953.1,
CCDS34172.1,
CCDS3990.1,
CCDS58954.1,
CCDS58951.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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