| Type | Description |
|---|---|
| Definition | apolipoprotein B receptor |
| Date | Results | Publications |
|---|---|---|
| 2019-02-02 11:15:00 | the findings reported here demonstrated that patients with mutations in FASN (c.G7192T, p.A2398S) and APOBR (c.C1883G, p.T628R) may be predisposed to hypothyroidism. These mutations may disrupt the regulation of fatty acid biosynthesis and lipid metabolism. These findings may reveal the high degree of genetic heterogeneity in hypothyroidism phenotypes. | 30272292 |
| 2014-01-18 10:37:00 | The obesity risk alleles of non-synonymous SNPs at SH2B1 and APOB48R have no strong effect on weight loss-related phenotypes in overweight children after a 1-year lifestyle intervention. | 23519644 |
| 2012-03-31 11:48:00 | These findings suggest that APOB48R represents a molecular target of postprandial lipoproteins via PPAR-dependent pathways in human monocytes and macrophages and advance an important link between postprandial metabolism of dietary fats and atherogenesis. | 22190030 |
| 2011-07-16 10:36:00 | investigation of apoB48R gene transcription in circulating monocytes: increase in apoB48R gene transcription following high-fat meal | 21367954 |
| 2010-01-21 00:00:00 | Atherogenic remnant lipoproteins induced macrophage foam cell formation via apoB48R, indicating a potential role of apoB48R in atherosclerosis. | 15591219 |
| Type | IDs |
|---|---|
| Synonymous | APOB100R, APOB48R |
| Gene |
UniProtKB-ID:
APOBR_HUMAN
UniprotKB:
Q0VD83
UniParc:
UPI00033362A0,
UPI00110C7285,
UPI000013EFFC
EMBL:
AF141332,
AF141333,
BC119788,
AK075085,
BC119786,
AC138894
Ensembl:
ENSG00000184730
KO:
hsa:55911
|
| Nucleutide sequences |
EMBL-CDS:
AAI19789.1,
AAF76256.1,
AAF76255.1,
AAI19787.1
Ensembl_TRS:
ENST00000564831
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000457539
RefSeq:
NP_061160.3
|
| Others |
UniRef100:
UniRef100_Q0VD83
UniRef90:
UniRef90_Q0VD83
UniRef50:
UniRef50_Q0VD83
UniGene:
Hs.200333
CCDS:
CCDS58442.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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