| Type | Description |
|---|---|
| Definition | protein kinase, DNA-activated, catalytic subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:36:00 | Deciphering the role of distinct DNA-PK phosphorylations at collapsed replication forks. | 32674014 |
| 2021-03-27 14:45:00 | Inhibition of miR-1193 leads to synthetic lethality in glioblastoma multiforme cells deficient of DNA-PKcs. | 32732911 |
| 2021-03-13 13:21:00 | Dimers of DNA-PK create a stage for DNA double-strand break repair. | 33077952 |
| 2021-03-13 13:19:00 | HUWE1-dependent DNA-PKcs neddylation modulates its autophosphorylation in DNA damage response. | 32457294 |
| 2021-03-06 13:30:00 | Structure of an activated DNA-PK and its implications for NHEJ. | 33385326 |
| Type | IDs |
|---|---|
| Synonymous | DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, IMD26, XRCC7, p350 |
| Gene |
UniProtKB-ID:
PRKDC_HUMAN
UniprotKB:
P78527
UniParc:
UPI0000213DD1,
UPI0000013593
EMBL:
U63630,
U34994,
L27425,
AY030284,
AY316117,
U35835,
U47077,
AB208860,
U90415,
AB052953
Ensembl:
ENSG00000253729
KO:
hsa:5591
|
| Nucleutide sequences |
EMBL-CDS:
AAC52019.2,
AAB51722.1,
BAB79635.1,
BAD92097.1,
AAA79244.1,
AAK40350.1,
AAA79184.1,
AAC50210.3,
AAP69525.1,
AAB39925.5
Ensembl_TRS:
ENST00000338368,
ENST00000314191
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000313420,
ENSP00000345182
RefSeq:
NP_001075109.1,
NP_008835.5
|
| Others |
UniRef100:
UniRef100_P78527
UniRef90:
UniRef90_P78527
UniRef50:
UniRef50_P78527
UniGene:
Hs.491682
CCDS:
CCDS75735.1,
CCDS75734.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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