| Type | Description |
|---|---|
| Definition | lysine methyltransferase 2E |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:34:00 | ODLURO syndrome: personal experience and review of the literature. | 32691224 |
| 2020-03-14 12:34:00 | Heterozygous Variants in KMT2E Cause a Spectrum of Neurodevelopmental Disorders and Epilepsy. | 31079897 |
| 2019-01-12 10:06:00 | In the duloxetine-treated subsample (N=186), we observed suggestive associations with ZNF385D (rs4261893; beta=-0.46, P=1.55 x 10(-5)), NCAM1 (rs2303377; beta=0.45, P=1.76 x 10(-5)) and MLL5 (rs117986340; beta=0.91, P=3.04 x 10(-5)). | 28696415 |
| 2017-07-08 11:22:00 | three dimensional structure of MLL5 SET domain unveils the structural basis for its lack of methyltransferase activity | 27812132 |
| 2016-08-20 10:10:00 | MLL5 preserves spindle bipolarity through maintaining cytosolic PLK1 in a nonaggregated form. | 27002166 |
| Type | IDs |
|---|---|
| Synonymous | HDCMC04P, MLL5, NKp44L |
| Gene |
UniProtKB-ID:
KMT2E_HUMAN
UniprotKB:
Q8IZD2
UniParc:
UPI0003F057C8,
UPI0001750280,
UPI00004245A1,
UPI000007448C,
UPI0001750281,
UPI0000074133,
UPI0000225637,
UPI000175027F
EMBL:
BC001296,
BC142987,
AC005070,
AY234382,
AY222296,
BC062583,
AY438698,
AC007384,
BC053906,
JQ809698,
AC005065,
BC040004,
AY195568,
AK000940,
AY195569,
AY147037,
AY157990,
CH471070,
AF519459
Ensembl:
ENSG00000005483
KO:
hsa:55904
|
| Nucleutide sequences |
EMBL-CDS:
AAH40004.1,
AAO89072.1,
AAN17675.1,
AAO64395.1,
AAO47009.1,
AAM74947.1,
AGE34449.1,
EAW83356.1,
AAO47010.1,
AAN76325.1,
AAH62583.1,
AAR13893.1,
AAH53906.1,
AAI42988.1,
AAH01296.1
Ensembl_TRS:
ENST00000311117,
ENST00000334884,
ENST00000476671,
ENST00000257745
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000312379,
ENSP00000417888,
ENSP00000335398,
ENSP00000257745
RefSeq:
NP_891847.1,
XP_024302605.1,
NP_061152.3,
XP_011514702.1,
XP_005250550.1,
XP_016867924.1
|
| Others |
UniRef100:
UniRef100_Q8IZD2
UniRef90:
UniRef90_Q8IZD2
UniRef50:
UniRef50_Q8IZD2
UniGene:
Hs.592262
CCDS:
CCDS34723.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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