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5590 PRKCZ

5590

PRKCZ

protein kinase C zeta

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein kinase C zeta

研究结论

Date Results Publications
2021-03-20 13:31:00 A polybasic domain in mediates Par6-dependent control of membrane targeting and kinase activity. 32580209
2021-02-27 13:49:00 Mitochondrial nucleoid remodeling and biogenesis are regulated by the pathway in p16(INK4a)-silenced cells. 32330121
2021-02-20 13:31:00 Bone metastatic breast cancer cells display downregulation of with enhanced glutamine metabolism. 33444686
2020-03-21 10:35:00 Intracellular sphingosine 1-phosphate (S1P) directly bound to the purified kinase domain of atypical protein kinase C isozymes (aduanyu1531) and relieved autoinhibitory constraints, thereby activating the kinase. 30600259
2019-12-14 10:18:00 Indomethacin impairs mitochondrial dynamics by activating the pathway and inducing apoptosis in gastric cancer and normal mucosal cells. 30940726

名称对应

Type IDs
Synonymous PKC-ZETA, PKC2
Gene
UniProtKB-ID: KPCZ_HUMAN
UniprotKB: Q05513
UniParc: UPI0000469EA1, UPI0001D3BC57, UPI0000169EB7
EMBL: AK294782, AL590822, BC014270, BT007082, Z15108, BC008058, AK294649, AL162271, AL645703, AK290995, L14283, AL391845
Ensembl: ENSG00000067606
KO: hsa:5590
Nucleutide sequences
EMBL-CDS: CAA78813.1, BAF83684.1, BAH11883.1, BAH11833.1, AAH14270.1, AAA36488.1, AAH08058.1, AAP35745.1
Ensembl_TRS: ENST00000400921, ENST00000461106, ENST00000378567
Protein sequencees
Ensembl_PRO: ENSP00000426412, ENSP00000383712, ENSP00000367830
RefSeq: XP_016857292.1, XP_016857279.1, XP_011540075.1, NP_001028754.1, XP_016857286.1, NP_002735.3, XP_024304158.1, XP_016857290.1, XP_016857278.1, XP_011540078.1, NP_001028753.1, XP_016857281.1, NP_001337735.1, XP_024304164.1, XP_016857282.1, XP_016857291.1, XP_024304159.1, XP_016857289.1, XP_024304165.1, NP_001229803.1, NP_001337732.1, XP_011540076.1, XP_011540077.1, NP_001337734.1, NP_001337733.1
Others
UniRef100: UniRef100_Q05513
UniRef90: UniRef90_Q05513
UniRef50: UniRef50_P09217
UniGene: Hs.496255
CCDS: CCDS37.1, CCDS55563.1, CCDS41229.1

全选

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