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5588 PRKCQ

5588

PRKCQ

protein kinase C theta

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein kinase C theta

研究结论

Date Results Publications
2021-03-20 13:27:00 axis via upregulation of VEGFR3 expression mediates hypoxia-induced pathological retinal neovascularization. 32382040
2021-02-20 13:36:00 Annexin A5 is essential for translocation during T-cell activation. 32796034
2020-11-21 13:26:00 PRKCQ inhibition enhances chemosensitivity of triple-negative breast cancer by regulating Bim. 32600444
2020-08-22 15:25:00 Two novel pleiotropic loci associated with osteoporosis and abdominal obesity. 32239398
2020-07-04 10:59:00 These findings demonstrate that plays an important role in a positive feedback regulatory loop that modulates TCR-proximal signaling and, moreover, provide a mechanistic explanation for earlier reports that documented an important role for duanyu1531theta; in T cell Ca(2+) signaling. This interaction could potentially serve as a promising and highly selective immunosuppressive drug target in autoimmu... 30992398

名称对应

Type IDs
Synonymous PRKCT, nPKC-theta
Gene
UniProtKB-ID: KPCT_HUMAN
UniprotKB: Q04759
UniParc: UPI00017A701C, UPI00004DC51A, UPI000012DF74
EMBL: L07032, AL158043, L01087, BC113359, BC101465, AK293935, AY702977, AL137145
Ensembl: ENSG00000065675
KO: hsa:5588
Nucleutide sequences
EMBL-CDS: AAI01466.1, BAG57313.1, AAI13360.1, AAA60101.1, AAA75571.1, AAU29340.1
Ensembl_TRS: ENST00000263125, ENST00000397176, ENST00000539722
Protein sequencees
Ensembl_PRO: ENSP00000263125, ENSP00000441752, ENSP00000380361
RefSeq: NP_001310195.1, NP_001229342.1, XP_024303844.1, NP_006248.1, NP_001310194.1, NP_001269574.1, NP_001310196.1, NP_001269573.1, XP_005252553.1, XP_005252554.1, XP_024303845.1
Others
UniRef100: UniRef100_Q04759
UniRef90: UniRef90_Q04759
UniRef50: UniRef50_Q04759
UniGene: Hs.498570
CCDS: CCDS60482.1, CCDS7079.1, CCDS55701.1

全选

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研究热度

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