| Type | Description |
|---|---|
| Definition | PDZ binding kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:14:00 | PBK Expression Is Associated With Prognosis of Patients With Oral Squamous Cell Carcinoma Treated With Radiotherapy: A Retrospective Study. | 33813430 |
| 2021-02-27 13:45:00 | Activation of NF-kappaB by TOPK upregulates Snail/Slug expression in TGF-beta1 signaling to induce epithelial-mesenchymal transition and invasion of breast cancer cells. | 32828273 |
| 2020-12-26 13:12:00 | A novel loss-of-function mutation of PBK associated with human kidney stone disease. | 32581305 |
| 2020-11-28 13:17:00 | Suppression of the solar ultraviolet-induced skin carcinogenesis by TOPK inhibitor HI-TOPK-032. | 32277233 |
| 2020-08-22 15:31:00 | Targeting the COX2/MET/TOPK signaling axis induces apoptosis in gefitinib-resistant NSCLC cells. | 31611604 |
| Type | IDs |
|---|---|
| Synonymous | CT84, HEL164, Nori-3, SPK, TOPK |
| Gene |
UniProtKB-ID:
TOPK_HUMAN,
V9HWH0_HUMAN
UniprotKB:
Q96KB5,
V9HWH0
UniParc:
UPI00017A831B,
UPI0000035B8B
EMBL:
CH471080,
AB027250,
AF189722,
AK027291,
EU794685,
AF237709,
AB027249,
AC104997,
BC015191,
AK301836
Ensembl:
ENSG00000168078
KO:
hsa:55872
|
| Nucleutide sequences |
EMBL-CDS:
BAG63280.1,
EAW63537.1,
EAW63536.1,
BAA99576.1,
AAF71521.1,
AAH15191.1,
AAF69107.1,
BAB55019.1,
BAA99577.1,
ACJ13739.1
Ensembl_TRS:
ENST00000522944,
ENST00000301905
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000301905,
ENSP00000428489
RefSeq:
NP_060962.2,
NP_001265874.1,
NP_001349969.1
|
| Others |
UniRef100:
UniRef100_Q96KB5
UniRef90:
UniRef90_Q96KB5
UniRef50:
UniRef50_Q96KB5
UniGene:
Hs.104741
CCDS:
CCDS6063.1,
CCDS64858.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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