| Type | Description |
|---|---|
| Definition | protein kinase D1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:38:00 | D1, Reduced in Human Pancreatic Tumors, Increases Secretion of Small Extracellular Vesicles From That Promote Metastasis to Lung in Mice. | 32446697 |
| 2020-11-21 13:20:00 | HDAC4 and 5 repression of TBX5 is relieved by protein kinase D1. | 31784580 |
| 2020-09-05 13:55:00 | A role for PKD1 in insulin secretion downstream of P2Y1 receptor activation in mouse and human islets. | 31591827 |
| 2020-07-25 12:01:00 | This study suggests a novel role of protein kinase D1 as a key modulator of the glucose metabolism in pancreatic cancer cells accelerating tumorigenesis and chemo-resistance. The remodelling of PKD1-dysregulated glucose metabolism can be achieved by regulation of mTORC1 for development of novel therapeutic strategies. | 31819177 |
| 2020-06-20 10:09:00 | Study demonstrated that protein kinase D1 (Prkd1) is a direct transcriptional target of Twist1 and is not expressed in the normal mammary epithelium. In patients with breast cancer, TWIST1 and PRKD1 expression correlated with metastatic recurrence. Data identify Prkd1 as a novel and targetable signaling node downstream of Twist1 that is required for epithelial invasion and dissemination. | 31676574 |
| Type | IDs |
|---|---|
| Synonymous | CHDED, PKC-MU, PKCM, PKD, PRKCM |
| Gene |
UniProtKB-ID:
KPCD1_HUMAN,
F8WBA3_HUMAN
UniprotKB:
Q15139,
F8WBA3
UniParc:
UPI0000456761,
UPI00020CDFDA
EMBL:
AL445884,
KF455850,
AL355053,
AL135858,
AK314170,
AL121840,
AL356756,
AL133372,
CH471078,
X75756
Ensembl:
ENSG00000184304
KO:
hsa:5587
|
| Nucleutide sequences |
EMBL-CDS:
BAG36853.1,
EAW65971.1,
CAA53384.1
Ensembl_TRS:
ENST00000616995,
ENST00000331968,
ENST00000415220
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000333568,
ENSP00000482645,
ENSP00000390535
RefSeq:
NP_002733.2,
NP_001316998.1,
XP_016876951.1,
NP_001335319.1,
XP_011535267.1
|
| Others |
UniRef100:
UniRef100_F8WBA3,
UniRef100_Q15139
UniRef90:
UniRef90_Q15139
UniRef50:
UniRef50_Q15139
UniGene:
Hs.508999
CCDS:
CCDS9637.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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