| Type | Description |
|---|---|
| Definition | histone deacetylase 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | Histone deacetylase 8 inhibition suppresses mantle cell lymphoma viability while preserving natural killer cell function. | 33190829 |
| 2021-04-13 10:09:00 | HDAC8-dependent deacetylation of PKM2 directs nuclear localization and glycolysis to promote proliferation in hepatocellular carcinoma. | 33279948 |
| 2021-01-02 12:50:00 | FLT3 inhibition upregulates HDAC8 via FOXO to inactivate p53 and promote maintenance of FLT3-ITD+ acute myeloid leukemia. | 32315388 |
| 2020-12-19 13:37:00 | miR-483-3p suppresses the proliferation and progression of human triple negative breast cancer cells by targeting the HDAC8>oncogene. | 31508813 |
| 2020-12-12 13:26:00 | AMPK-dependent phosphorylation of HDAC8 triggers PGM1 expression to promote lung cancer cell survival under glucose starvation. | 32171858 |
| Type | IDs |
|---|---|
| Synonymous | CDA07, CDLS5, HD8, HDACL1, KDAC8, MRXS6, RPD3, WTS |
| Gene |
UniProtKB-ID:
HDAC8_HUMAN
UniprotKB:
Q9BY41
UniParc:
UPI00017A7467,
UPI000059DB5E,
UPI000059DB5B,
UPI000059DB56,
UPI000059DB58,
UPI00000411E6
EMBL:
BX295542,
AF230097,
AF245664,
T99283,
AK300895,
AF212246,
AL133500,
AK296641,
AA376331,
AJ277724,
BQ189619,
AI159768,
BC050433
Ensembl:
ENSG00000147099
KO:
hsa:55869
|
| Nucleutide sequences |
EMBL-CDS:
CAB90213.1,
BAG59242.1,
AAF73076.1,
AAF73428.1,
AAH50433.1,
BAG62534.1,
AAK14930.1
Gene_ORFName:
CDA07
Ensembl_TRS:
ENST00000373559,
ENST00000649116,
ENST00000373589,
ENST00000373554,
ENST00000373556,
ENST00000373573,
ENST00000439122
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000414486,
ENSP00000497925,
ENSP00000362691,
ENSP00000362660,
ENSP00000362657,
ENSP00000362655,
ENSP00000362674
RefSeq:
XP_016885136.2,
NP_001159894.1,
XP_016885133.1,
XP_016885135.1,
XP_016885134.1,
NP_001159892.1,
XP_011529288.3,
XP_016885132.1,
XP_016885129.2,
NP_001159891.1,
NP_001159920.1,
NP_060956.1,
XP_024308173.1,
XP_016885130.2,
NP_001159890.1,
XP_016885131.1
|
| Others |
UniRef100:
UniRef100_Q9BY41
UniRef90:
UniRef90_Q9BY41
UniRef50:
UniRef50_Q9BY41
UniGene:
Hs.310536
CCDS:
CCDS55450.1,
CCDS55451.1,
CCDS55449.1,
CCDS14420.1,
CCDS55448.1,
CCDS55452.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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