| Type | Description |
|---|---|
| Definition | presenilin enhancer, gamma-secretase subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:34:00 | Super-resolution microscopy reveals majorly mono- and dimeric presenilin1/gamma-secretase at the cell surface. | 32631487 |
| 2019-10-05 12:17:00 | Modulation of the PSENEN trafficking pathway might be a potential target for the development of Abeta42-lowering Alzheimer disease therapeutics | 29851073 |
| 2019-05-18 10:30:00 | No mutation that was likely to be pathogenic for acne inversa was found in PSEN1 or PSENEN in any participant. | 30105992 |
| 2019-04-27 10:45:00 | The present study further expands the spectrum of PSENEN mutations associated with HS-DDD and suggests a role for Notch signalling in the pathogenesis of this intriguing combined disorder. | 28922471 |
| 2018-09-22 10:44:00 | High gamma-secretase expression is associated with head and neck squamous cell carcinoma. | 29047105 |
| Type | IDs |
|---|---|
| Synonymous | ACNINV2, MDS033, MSTP064, PEN-2, PEN2 |
| Gene |
UniProtKB-ID:
PEN2_HUMAN
UniprotKB:
Q9NZ42
UniParc:
UPI000006FFC1
EMBL:
BC009575,
AK312233,
AF220053
Ensembl:
ENSG00000205155
KO:
hsa:55851
|
| Nucleutide sequences |
EMBL-CDS:
AAF67646.1,
BAG35166.1,
AAH09575.1
Gene_ORFName:
MDS033
Ensembl_TRS:
ENST00000222266,
ENST00000587708
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000468411,
ENSP00000222266
RefSeq:
NP_758844.1,
NP_001268461.1
|
| Others |
UniRef100:
UniRef100_Q9NZ42
UniRef90:
UniRef90_Q9NZ42
UniRef50:
UniRef50_Q9NZ42
UniGene:
Hs.534465
CCDS:
CCDS12474.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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