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5585 PKN1

5585

PKN1

protein kinase N1

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein kinase N1

研究结论

Date Results Publications
2020-11-28 13:11:00 Novel roles of PRK1 and PRK2 in cilia and cancer biology. 32127582
2020-06-06 11:14:00 Characterization of the novel cardiolipin binding regions identified on the protease and lipid activated kinase 1 31125460
2020-03-28 10:50:00 Secretory carcinoma of the skin associated with the presence of novel NFIX-PKN1 translocation. 31045890
2020-01-04 12:18:00 PKN1 transduces androgen-responsiveness to serum response factor in prostate neoplasms 30742064
2018-01-13 12:02:00 Steady-state kinetic analysis revealed that PKN1-3 follows a sequential ordered Bi-Bi kinetic mechanism, where peptide substrate binding is preceded by ATP binding. This kinetic mechanism was confirmed by additional kinetic studies for product inhibition and affinity of small molecule inhibitors. 27919031

名称对应

Type IDs
Synonymous DBK, PAK-1, PAK1, PKN, PKN-ALPHA, PRK1, PRKCL1
Gene
UniProtKB-ID: PKN1_HUMAN
UniprotKB: Q16512
UniParc: UPI000013CB15, UPI000050D034, UPI0000366D4D
EMBL: BC094766, AC008569, BC040061, AK292130, AK313886, AK123007, U33053, S75546, D26181
Ensembl: ENSG00000123143
KO: hsa:5585
Nucleutide sequences
EMBL-CDS: AAH40061.1, AAB33345.1, AAH94766.1, AAC50209.1, BAG36611.1, BAA05169.1, BAG53845.1, BAF84819.1
Ensembl_TRS: ENST00000342216, ENST00000242783
Protein sequencees
Ensembl_PRO: ENSP00000343325, ENSP00000242783
RefSeq: NP_998725.1, NP_002732.3
Others
UniRef100: UniRef100_Q16512
UniRef90: UniRef90_Q16512
UniRef50: UniRef50_Q16512
UniGene: Hs.466044
CCDS: CCDS42513.1, CCDS42514.1

全选

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研究热度

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