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55845 BRK1

55845

BRK1

BRICK1 subunit of SCAR/WAVE actin nucleating complex

protein-coding

Homo sapiens

基因描述

Type Description
Definition BRICK1 subunit of SCAR/WAVE actin nucleating complex

研究结论

Date Results Publications
2014-06-28 12:46:00 Sp1 transcriptionally regulates BRK1 expression in non-small cell lung cancer cells. 24680773
2013-11-02 10:57:00 We verified that NRF-1 positively regulates FAM134C and ENOX1, and negatively regulates C3orf10 in human neuroblastoma IMR-32 cells and primary rat cortical neurons. 23939472
2011-02-12 10:07:00 Data show that Brk1 downregulation results in defective directional migration and invasive growth in renal cell carcinoma cells as well as in other tumor cell types. 20861187
2010-01-21 00:00:00 Von Hippel-Lindau (VHL) locus deletion of the HSPC300 actin regulator gene greatly lowers risk of clear cell renal cell carcinoma development in Spanish VHL syndrome patients studied. 17311301
2010-01-21 00:00:00 Growing body of evidence suggesting that patients with VHL syndrome caused by large VHL deletions that include C3orf10 may be designated as having a specific subtype (Type 1B) of the disorder. 19764026

名称对应

Type IDs
Synonymous C3orf10, HSPC300, MDS027, hHBrk1
Gene
UniProtKB-ID: BRK1_HUMAN
UniprotKB: Q8WUW1
UniParc: UPI0000F53469, UPI0000049C9A
EMBL: BC019303, AK312155, CH471055, BC007929, AY148220, BC001067, AY148219, AF161418
Ensembl: ENSG00000254999
KO: hsa:55845
Nucleutide sequences
EMBL-CDS: AAN60162.1, AAN60161.1, EAW64061.1, AAH19303.1, BAG35089.1, AAH07929.1, AAH01067.1, AAF28978.1
Gene_ORFName: MDS027, HSPC300
Ensembl_TRS: ENST00000530758
Protein sequencees
Ensembl_PRO: ENSP00000432472
RefSeq: NP_060932.2
Others
UniRef100: UniRef100_Q8WUW1
UniRef90: UniRef90_Q8WUW1
UniRef50: UniRef50_Q8WUW1
UniGene: Hs.649307
CCDS: CCDS54553.1

全选

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