| Type | Description |
|---|---|
| Definition | ELL associated factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-03 12:11:00 | EAF2 frameshift mutation is associated with Colorectal Cancer. | 30088132 |
| 2019-06-08 12:11:00 | Findings provide further evidence that ELL2 is a potential tumor suppressor frequently down-regulated in clinical prostate cancer specimens and provides new insights into regulation of ELL2 protein level by polyubiquitination and EAF2 binding. | 30009504 |
| 2018-12-01 10:04:00 | Simultaneous inactivation of EAF2 and p53 can act to activate and drive prostate tumorigenesis. | 29518696 |
| 2018-07-28 11:11:00 | The results indicated that Eaf2 was able to effectively suppress H2O2induced apoptosis of HLE cells via inhibition of caspase 3 production and activation of Wnt3a signaling. | 29257273 |
| 2018-02-10 10:05:00 | EZH2 promotes tumorigenesis and malignant progression in part by activating glycolysis through an EAF2-HIF1alpha signaling axis. | 27259264 |
| Type | IDs |
|---|---|
| Synonymous | BM040, TRAITS, U19 |
| Gene |
UniProtKB-ID:
EAF2_HUMAN,
B4DWJ3_HUMAN
UniprotKB:
Q96CJ1,
B4DWJ3
UniParc:
UPI00017A808E,
UPI000000D7DA,
UPI000006EBB1
EMBL:
AY049020,
BC014209,
AF217516,
AC072031,
AF517829,
AC119736,
AK301560
Ensembl:
ENSG00000145088
KO:
hsa:55840
|
| Nucleutide sequences |
EMBL-CDS:
AAO63811.1,
AAH14209.1,
AAL12223.1,
AAF67627.1,
BAG63055.1
Gene_ORFName:
BM-040
Ensembl_TRS:
ENST00000273668,
ENST00000451944
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000273668,
ENSP00000410708
RefSeq:
NP_060926.2,
NP_001306970.1,
XP_016862352.1,
XP_016862350.1,
XP_005247675.1,
XP_016862351.1
|
| Others |
UniRef100:
UniRef100_B4DWJ3,
UniRef100_Q96CJ1
UniRef90:
UniRef90_Q96CJ1
UniRef50:
UniRef50_Q96CJ1
UniGene:
Hs.477325
CCDS:
CCDS3006.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员