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5583 PRKCH

5583

PRKCH

protein kinase C eta

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein kinase C eta

研究结论

Date Results Publications
2020-10-03 12:51:00 PRKCH polymorphism is associated with rheumatoid arthritis in a Chinese population. 31875586
2020-07-25 12:41:00 Study provides mechanistic evidence that inhibition of isoform alleviated mitochondrial injuries and function, attenuated apoptosis, and renal fibrosis in high glucose (HG)-cultured advanced oxidation protein products (AOPPs)-induced HK-2 cells. Thus, AOPPs-induced mitochondrial dysfunction and oxidative stress cause tubulointerstitial fibrosis in diabetic nephropathy via activation of the duanyu1531eta isoform. 29482336
2020-04-11 12:38:00 The author show that knockdown of caused resistance to chemotherapeutic drug-induced apoptosis and this could be explained by the induction of cellular senescence. 30562553
2018-06-16 10:36:00 These results suggest that utilizes the ERK signaling pathway to protect against ubiquitin-mediated proteasomal degradation of Mcl-1 28939105
2018-05-19 10:05:00 PRKCH rs2230500 gene polymorphism is significantly related to the efficiency in telmisartan therapy (p = 0.02). The PRKCH rs2230500 may influence the antihypertensive efficacy of telmisartan in Chinese EH patients. 28640647

名称对应

Type IDs
Synonymous PKC-L, PKCL, PRKCL, nPKC-eta
Gene
UniProtKB-ID: KPCL_HUMAN
UniprotKB: P24723
UniParc: UPI0000073BBF, UPI00001B24A6
EMBL: AL359220, BC037268, AK290183, AL355916, AL138996, CH471061, AK296158, S74620, M55284
Ensembl: ENSG00000027075
KO: hsa:5583
Nucleutide sequences
EMBL-CDS: AAA60100.1, AAB32724.1, EAW80800.1, AAH37268.1, EAW80801.1, BAF82872.1, BAG58897.1
Ensembl_TRS: ENST00000332981, ENST00000555082
Protein sequencees
Ensembl_PRO: ENSP00000450981, ENSP00000329127
RefSeq: XP_016876948.1, XP_024305429.1, XP_011535259.1, XP_011535257.1, XP_011535258.1, XP_011535256.1, XP_016876947.1, XP_024305430.1, NP_006246.2
Others
UniRef100: UniRef100_P24723
UniRef90: UniRef90_P24723
UniRef50: UniRef50_P24723
UniGene: Hs.333907
CCDS: CCDS9752.1

全选

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