FGD6 - FYVE, RhoGEF and PH domain containing 6-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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55785 FGD6

基因描述

Type	Description
Definition	FYVE, RhoGEF and PH domain containing 6

研究结论

Date	Results	Publications
2017-07-01 12:50:00	data suggest that oxidized phospholipids and FGD6-Arg329 might act synergistically to increase susceptibility to PCV	27089177

名称对应

Type	IDs
Synonymous	ZFYVE24
Gene	UniProtKB-ID: FGD6_HUMAN UniprotKB: Q6ZV73 UniParc: UPI00001FB2F4, UPI0001B9E74F EMBL: BC013319, AK128492, AK002045, AK124904, BX538322, AB037783 Ensembl: ENSG00000180263 KO: hsa:55785
Nucleutide sequences	EMBL-CDS: BAC87464.1, BAA92600.1, AAH13319.2, BAC85990.1, BAA92052.1, CAD98096.1 Ensembl_TRS: ENST00000546711, ENST00000343958
Protein sequencees	Ensembl_PRO: ENSP00000344446, ENSP00000450342 RefSeq: NP_060821.3
Others	UniRef100: UniRef100_Q6ZV73 UniRef90: UniRef90_Q6ZV73 UniRef50: UniRef50_Q6ZV73 UniGene: Hs.506381 CCDS: CCDS31878.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32203420	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions. Nat. Cell Biol. Paul M MÃ¼ller , Juliane Rademacher , Richard D Bagshaw , Celina Wortmann , Carolin Barth , Jakobus van Unen , Keziban M Alp , Girolamo Giudice , Rebecca L Eccles , Louise E Heinrich , Patricia Pascual-Vargas , Marta Sanchez-Castro , Lennart Brandenburg , Geraldine Mbamalu , Monika Tucholska , Lisa Spatt , Maciej T Czajkowski , Robert-William Welke , Sunqu Zhang , Vivian Nguyen , Trendelina Rrustemi , Philipp Trnka , Kiara Freitag , Brett Larsen , Oliver Popp , Philipp Mertins , Anne-Claude Gingras , Frederick P Roth , Karen Colwill , Chris Bakal , Olivier Pertz , Tony Pawson , Evangelia Petsalaki , Oliver Rocks	2020-04-01	-
31586073	The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis. Nat Commun Luisa Capalbo , Zuni I Bassi , Marco Geymonat , Sofia Todesca , Liviu Copoiu , Anton J Enright , Giuliano Callaini , Maria Giovanna Riparbelli , Lu Yu , Jyoti S Choudhary , Enrico Ferrero , Sally Wheatley , Max E Douglas , Masanori Mishima , Pier Paolo D'Avino	2019-10-04	-
30639242	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2. Mol. Cell Joanna R Kovalski , Aparna Bhaduri , Ashley M Zehnder , Poornima H Neela , Yonglu Che , Glenn G Wozniak , Paul A Khavari	2019-02-21	-
30021884	Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Mol Cell Proteomics Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck	2018-10-01	-
29987050	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. Proc. Natl. Acad. Sci. U.S.A. Tengfei Xiao , Wei Li , Xiaoqing Wang , Han Xu , Jixin Yang , Qiu Wu , Ying Huang , Joseph Geradts , Peng Jiang , Teng Fei , David Chi , Chongzhi Zang , Qi Liao , Jonathan Rennhack , Eran Andrechek , Nanlin Li , Simone Detre , Mitchell Dowsett , Rinath M Jeselsohn , X Shirley Liu , Myles Brown	2018-07-31	-
29507755	VIRMA mediates preferential m⁶A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov Yanan Yue , Jun Liu , Xiaolong Cui , Jie Cao , Guanzheng Luo , Zezhou Zhang , Tao Cheng , Minsong Gao , Xiao Shu , Honghui Ma , Fengqin Wang , Xinxia Wang , Bin Shen , Yizhen Wang , Xinhua Feng , Chuan He , Jianzhao Liu	2018-01-01	-
29117863	RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. BMC Biol Nila Roy Choudhury , Gregory Heikel , Maryia Trubitsyna , Peter Kubik , Jakub Stanislaw Nowak , Shaun Webb , Sander Granneman , Christos Spanos , Juri Rappsilber , Alfredo Castello , Gracjan Michlewski	2017-11-08	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
27089177	A missense variant in FGD6 confers increased risk of polypoidal choroidal vasculopathy. Nat. Genet. Lulin Huang , Houbin Zhang , Ching-Yu Cheng , Feng Wen , Pancy O S Tam , Peiquan Zhao , Haoyu Chen , Zheng Li , Lijia Chen , Zhengfu Tai , Kenji Yamashiro , Shaoping Deng , Xianjun Zhu , Weiqi Chen , Li Cai , Fang Lu , Yuanfeng Li , Chui-Ming G Cheung , Yi Shi , Masahiro Miyake , Yin Lin , Bo Gong , Xiaoqi Liu , Kar-Seng Sim , Jiyun Yang , Keisuke Mori , Xiongzhe Zhang , Peter D Cackett , Motokazu Tsujikawa , Kohji Nishida , Fang Hao , Shi Ma , He Lin , Jing Cheng , Ping Fei , Timothy Y Y Lai , Sibo Tang , Augustinus Laude , Satoshi Inoue , Ian Y Yeo , Yoichi Sakurada , Yu Zhou , Hiroyuki Iijima , Shigeru Honda , Chuntao Lei , Lin Zhang , Hong Zheng , Dan Jiang , Xiong Zhu , Tien-Ying Wong , Chiea-Chuen Khor , Chi-Pui Pang , Nagahisa Yoshimura , Zhenglin Yang	2016-06-01	-
27173435	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Nat Commun Karsten Boldt , Jeroen van Reeuwijk , Qianhao Lu , Konstantinos Koutroumpas , Thanh-Minh T Nguyen , Yves Texier , Sylvia E C van Beersum , Nicola Horn , Jason R Willer , Dorus A Mans , Gerard Dougherty , Ideke J C Lamers , Karlien L M Coene , Heleen H Arts , Matthew J Betts , Tina Beyer , Emine Bolat , Christian Johannes Gloeckner , Khatera Haidari , Lisette Hetterschijt , Daniela Iaconis , Dagan Jenkins , Franziska Klose , Barbara Knapp , Brooke Latour , Stef J F Letteboer , Carlo L Marcelis , Dragana Mitic , Manuela Morleo , Machteld M Oud , Moniek Riemersma , Susan Rix , Paulien A Terhal , Grischa Toedt , Teunis J P van Dam , Erik de Vrieze , Yasmin Wissinger , Ka Man Wu , Gordana Apic , Philip L Beales , Oliver E Blacque , Toby J Gibson , Martijn A Huynen , Nicholas Katsanis , Hannie Kremer , Heymut Omran , Erwin van Wijk , Uwe Wolfrum , FranÃ§ois Kepes , Erica E Davis , Brunella Franco , Rachel H Giles , Marius Ueffing , Robert B Russell , Ronald Roepman , UK10K Rare Diseases Group	2016-05-13	-

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