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55765 INAVA

55765

INAVA

innate immunity activator

protein-coding

Homo sapiens

基因描述

Type Description
Definition innate immunity activator

研究结论

Date Results Publications
2019-09-28 11:06:00 Study identifies C1ORF106 as an epithelial cell junction protein, and the loss of C1ORF106 augments TNF-alpha-induced intestinal epithelial leakage and diarrhea that may play a critical role in the development of inflammatory bowel disease. 31022698
2019-03-02 11:32:00 INAVA-CUPID exhibits dual functions, coordinated directly by ARNO, that bridge epithelial barrier function with extracellular signals and inflammation. 30355448
2018-05-05 11:20:00 C1orf106 regulates adherens junction stability by regulating the degradation of cytohesin-1, a guanine nucleotide exchange factor that controls activation of ARF6. 29420262
2017-09-30 10:30:00 IBD-associated polymorphisms in INAVA modulate PRR-initiated signaling, cytokines, and intracellular bacterial clearance, likely contributing to intestinal immune homeostasis. 28436939
2017-04-08 11:00:00 Results found that CpG sites of C1orf106, DMBX1, and SIK3 mediate the genetic risk of psoriasis in Chinese Han population. 27980695

名称对应

Type IDs
Synonymous C1orf106
Gene
UniProtKB-ID: INAVA_HUMAN
UniprotKB: Q3KP66
UniParc: UPI0000204714, UPI000013E26E
EMBL: AK001583, AC099756, AK001763, AK316510, BC106877, AK303885
Ensembl: ENSG00000163362
KO: hsa:55765
Nucleutide sequences
EMBL-CDS: BAA91892.1, AAI06878.1, BAA91771.1, BAH14881.1, BAG64821.1
Ensembl_TRS: ENST00000367342, ENST00000413687
Protein sequencees
Ensembl_PRO: ENSP00000356311, ENSP00000392105
RefSeq: NP_001354219.1, NP_001136041.1, XP_011508057.1, NP_001354218.1, NP_060735.4, XP_011508056.1, XP_011508058.1
Others
UniRef100: UniRef100_Q3KP66
UniRef90: UniRef90_Q3KP66
UniRef50: UniRef50_Q3KP66
UniGene: Hs.518997
CCDS: CCDS44292.1

全选

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研究热度

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