Type | Description |
---|---|
Definition | innate immunity activator |
Date | Results | Publications |
---|---|---|
2019-09-28 11:06:00 | Study identifies C1ORF106 as an epithelial cell junction protein, and the loss of C1ORF106 augments TNF-alpha-induced intestinal epithelial leakage and diarrhea that may play a critical role in the development of inflammatory bowel disease. | 31022698 |
2019-03-02 11:32:00 | INAVA-CUPID exhibits dual functions, coordinated directly by ARNO, that bridge epithelial barrier function with extracellular signals and inflammation. | 30355448 |
2018-05-05 11:20:00 | C1orf106 regulates adherens junction stability by regulating the degradation of cytohesin-1, a guanine nucleotide exchange factor that controls activation of ARF6. | 29420262 |
2017-09-30 10:30:00 | IBD-associated polymorphisms in INAVA modulate PRR-initiated signaling, cytokines, and intracellular bacterial clearance, likely contributing to intestinal immune homeostasis. | 28436939 |
2017-04-08 11:00:00 | Results found that CpG sites of C1orf106, DMBX1, and SIK3 mediate the genetic risk of psoriasis in Chinese Han population. | 27980695 |
Type | IDs |
---|---|
Synonymous | C1orf106 |
Gene |
UniProtKB-ID:
INAVA_HUMAN
UniprotKB:
Q3KP66
UniParc:
UPI0000204714,
UPI000013E26E
EMBL:
AK001583,
AC099756,
AK001763,
AK316510,
BC106877,
AK303885
Ensembl:
ENSG00000163362
KO:
hsa:55765
|
Nucleutide sequences |
EMBL-CDS:
BAA91892.1,
AAI06878.1,
BAA91771.1,
BAH14881.1,
BAG64821.1
Ensembl_TRS:
ENST00000367342,
ENST00000413687
|
Protein sequencees |
Ensembl_PRO:
ENSP00000356311,
ENSP00000392105
RefSeq:
NP_001354219.1,
NP_001136041.1,
XP_011508057.1,
NP_001354218.1,
NP_060735.4,
XP_011508056.1,
XP_011508058.1
|
Others |
UniRef100:
UniRef100_Q3KP66
UniRef90:
UniRef90_Q3KP66
UniRef50:
UniRef50_Q3KP66
UniGene:
Hs.518997
CCDS:
CCDS44292.1
|
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Refseq |
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