例如:"NBL1", "4681", "drought"
收藏
5576 PRKAR2A

5576

PRKAR2A

protein kinase cAMP-dependent type II regulatory subunit alpha

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein kinase cAMP-dependent type II regulatory subunit alpha

研究结论

Date Results Publications
2016-08-27 12:44:00 High PK-R2 expression is associated with colorectal cancer. 26372733
2016-07-02 10:56:00 Prkar2a deficiency predisposes to hematopoietic malignancies in vivo. RIIalpha's likely association with HS and DLBCL was hitherto unrecognized and may lead to better understanding of these rare neoplasms. 26608815
2016-05-28 10:06:00 Disruption of Snapin-PKR2 interaction did not affect PKR2 signaling, but increased the ligand-induced degradation, implying a role of Snapin in the trafficking of PKR2. 26687946
2015-12-12 10:22:00 we demonstrate that neurochondrin has strong isoform selectivity towards the RIIa subunit of with nanomolar affinity 25916936
2015-02-07 11:18:00 Results show that mouse Prkar1a and human PRKAR2A exhibited a dynamic spatio-temporal expression in tooth development, whereas neither human PRKAR1A nor mouse Prkar2a showed their expression in odontogenesis. 24755349

名称对应

Type IDs
Synonymous PKR2, PRKAR2
Gene
UniProtKB-ID: KAP2_HUMAN, A8KAH7_HUMAN, A0A024R2W3_HUMAN, A0A0S2Z472_HUMAN
UniprotKB: P13861, A8KAH7, A0A024R2W3, A0A0S2Z472
UniParc: UPI0000161B64, UPI0000071933, UPI00015DAABD
EMBL: BC002763, KU178276, CH471055, X14968, AK293042, BT007225, X99455, AC144546, AC141002, KU178277
Ensembl: ENSG00000114302
KO: hsa:5576
Nucleutide sequences
EMBL-CDS: CAA67817.1, CAA33094.1, EAW64927.1, AAH02763.1, AAP35889.1, EAW64926.1, BAF85731.1, ALQ33735.1, EAW64928.1, EAW64925.1, ALQ33734.1
Gene_ORFName: hCG_1779456
Ensembl_TRS: ENST00000454963, ENST00000265563, ENST00000296446
Protein sequencees
Ensembl_PRO: ENSP00000296446, ENSP00000265563, ENSP00000394041
RefSeq: NP_001308911.1, XP_011532244.1, NP_001308912.1, NP_004148.1, NP_001308918.1, XP_005265372.1, XP_011532245.1
Others
UniRef100: UniRef100_P13861-2, UniRef100_A8KAH7, UniRef100_P13861
UniRef90: UniRef90_P13861-2, UniRef90_P13861
UniRef50: UniRef50_P13861
UniGene: Hs.631923
CCDS: CCDS82771.1, CCDS2778.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员