| Type | Description |
|---|---|
| Definition | transmembrane protein 30A |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:54:00 | Crystal structure of a human plasma membrane phospholipid flippase. | 32493773 |
| 2020-07-25 11:54:00 | Highlights on a multifaceted role for TMEM30A in B-cell lymphomagenesis, and characterization of intrinsic and extrinsic vulnerabilities of cancer cells that can be therapeutically exploited. | 32094924 |
| 2020-06-27 11:24:00 | Mechanistically, deletion of TMEM30A caused reduced endothelial cell proliferation by inhibiting VEGF-induced signaling. The findings reveal essential roles of TMEM30A in angiogenesis, providing a potential therapeutic target. | 30814335 |
| 2019-02-02 12:08:00 | Identified TMEM30A as a candidate partner for beta-carboxyl-terminal fragment (betaCTF) of amyloid-beta precursor protein (APP). TMEM30A physically interacts with betaCTF in endosomes and may impair vesicular traffic, leading to abnormally enlarged endosomes. Data suggested that TMEM30A is involved in betaCTF-dependent endosome abnormalities that are related to Abeta overproduction. | 30086173 |
| 2018-12-22 10:13:00 | results indicated that the extracellular domain of CDC50A has important roles both in CDC50A's ability to chaperone ATP11C to the plasma membrane and in inducing ATP11C's ATP hydrolysis-coupled flippase activity. | 29276178 |
| Type | IDs |
|---|---|
| Synonymous | C6orf67, CDC50A |
| Gene |
UniProtKB-ID:
CC50A_HUMAN
UniprotKB:
Q9NV96
UniParc:
UPI0000414844,
UPI0000071AE1,
UPI000006E77A
EMBL:
AL832490,
AK292823,
AL080250,
AK001718,
AL162046,
BC009006,
AL832815,
CH471051
Ensembl:
ENSG00000112697
KO:
hsa:55754
|
| Nucleutide sequences |
EMBL-CDS:
AAH09006.1,
EAW48744.1,
CAH56262.1,
EAW48745.1,
BAF85512.1,
BAA91859.1,
EAW48743.1,
CAB82389.1,
CAH56205.1
Ensembl_TRS:
ENST00000475111,
ENST00000674151,
ENST00000370050,
ENST00000230461
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000230461,
ENSP00000500998,
ENSP00000359067,
ENSP00000431007
RefSeq:
NP_001137430.1,
NP_060717.1
|
| Others |
UniRef100:
UniRef100_Q9NV96
UniRef90:
UniRef90_Q9NV96
UniRef50:
UniRef50_Q9NV96
UniGene:
Hs.108530
CCDS:
CCDS4983.1,
CCDS47453.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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