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55750 AGK

55750

AGK

acylglycerol kinase

protein-coding

Homo sapiens

基因描述

Type Description
Definition acylglycerol kinase

研究结论

Date Results Publications
2021-02-20 13:29:00 The role of AGK in thrombocytopoiesis and possible therapeutic strategies. 32202634
2021-01-30 13:02:00 Acylglycerol kinase promotes tumour growth and metastasis via activating the PI3K/AKT/GSK3beta signalling pathway in renal cell carcinoma. 31900208
2020-06-20 11:39:00 miR-610 expression was significantly downregulated in both oral squamous cell carcinoma (OSCC) tissues and cell lines. Low miR-610 expression was associated with advanced T classification, TNM stage and poorer prognosis. Overexpression of miR-610 significantly suppressed OSCC cells proliferation, migration, invasion and EMT process. Mechanistically, AGK was confirmed to be the downstream target of miR-610 in OSCC cells. 30657560
2017-09-30 12:04:00 Identify AGK as a bona fide subunit of TIM22 providing an exciting and unexpected link between mitochondrial protein import and Sengers syndrome. 28712726
2017-09-30 12:04:00 The dual function of AGK as lipid kinase and constituent of the TIM22 complex reveals that disturbances in both phospholipid metabolism and mitochondrial protein biogenesis contribute to the pathogenesis of Sengers syndrome. 28712724

名称对应

Type IDs
Synonymous CATC5, CTRCT38, MTDPS10, MULK
Gene
UniProtKB-ID: AGK_HUMAN, A4D1U5_HUMAN
UniprotKB: Q53H12, A4D1U5
UniParc: UPI000006E622, UPI00000704D5
EMBL: AK222769, CH471070, CH236950, AC099547, AJ278150, BC022777, AK001704, BC009775, AC073878, AC004918
Ensembl: ENSG00000006530, ENSG00000262327
KO: hsa:55750
Nucleutide sequences
EMBL-CDS: AAH22777.1, BAA91848.1, AAS07537.1, BAD96489.1, AAH09775.1, CAB93536.1, EAW83972.1, EAL24020.1
Gene_ORFName: hCG_39451, tcag7.330
Ensembl_TRS: ENST00000575872, ENST00000492693, ENST00000650547, ENST00000649286, ENST00000648068
Protein sequencees
Ensembl_PRO: ENSP00000498112, ENSP00000418789, ENSP00000497280, ENSP00000458417, ENSP00000496789
RefSeq: NP_060708.1, XP_024302603.1, NP_001351877.1, XP_011514699.1
Others
UniRef100: UniRef100_Q53H12
UniRef90: UniRef90_Q53H12
UniRef50: UniRef50_Q53H12
UniGene: Hs.743318
CCDS: CCDS5865.1

全选

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